| structure name | CRYSTAL STRUCTURE OF OCT-1 POU DIMER BOUND TO MORE (OCTAMER-BINDING TRANSCRIPTION FACTOR 1) |
| reference | Schoeler et al. Mol.Cell 8 569 2001 |
| source | Homo sapiens |
| experiment | X-ray (resolution=1.90, R-factor=0.220) |
| structural superfamily | lambda repressor-like DNA-binding domains;Homeodomain-like; |
| sequence family | Pou domain Nterminal to homeobox domain; |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | SQTSRLNRVSNQR |
Estimated binding specificities ?
| readout + contact |  |
A | 9 96 0 0 9 67 0 C | 69 0 0 0 67 11 0 G | 9 0 0 96 11 9 0 T | 9 0 96 0 9 9 96scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: OCT-1 | ||
| ATGCAAAT | PubMed | 1e3o_C(1.67e-04), 1cqt_AI(8.38e-09), 1cqt_BJ(6.42e-13), ... (total=9) |
| ATTTGCAT | PubMed | 1e3o_C(1.67e-04), 1cqt_AI(8.38e-09), 1cqt_BJ(6.42e-13), ... (total=9) |
| TATGC | PubMed | 1e3o_C(1.01e-03), 1cqt_AI(4.06e-03), 1cqt_BJ(5.83e-06), ... (total=5) |
| GCTAGCAT | PubMed | 1e3o_C(5.22e-03), 1cqt_BJ(1.09e-02), 1gt0_CD(2.54e-04), ... (total=5) |
| AAATTAGCATGT | PubMed | 1e3o_C(1.57e-03), 1cqt_AI(4.65e-03), 1cqt_BJ(3.35e-05), ... (total=7) |
Dendrogram of similar interfaces ?
matrix format--SGQATT--STRG--LTNT--------RTVASTNAQA---- L +1e3o_C +----------4 --SGQATT--CTRG--LTNT--------RCVACTNAQA---- L ! +7xrc_C +--9 --------------------RA--------ITQTNAMG---- L ! ! +5zjt_E ! +----------2 --------------------RT--------NT--NAITRG-- L ! +5zjt_B ! --------------------RT--------IAKGNA------ L ! +2hdd_A +---11 +-1 ------------------------------IA--NA------ ! ! +----3 +4qtr_D ! ! ! ! --------------------RT--------NT--NAIARG-- L ! ! +-------8 +1b72_B ! ! ! ! --------------------RT------KTIAQCNA----RT L ! ! ! ! +1ig7_A ! +-10 +----5 --------------------RT--------ITQCNAACRG-- L +-------14 ! +6a8r_A ! ! ! --------------------RT--------NT--NA--RG-- L ! ! ! +1b8i_B ! ! +------------6 ------------------------------NCITNARGRG-- L ! ! +6fqq_E ! ! --------------------RA------KGSAQA-------- L ! ! +---------------6j5b_C +-16 +-13 --------------------RTSTVC--KGDCRG-------- L ! ! ! +-1w0t_A ! ! +-------------7 --------------------RT--RTQT--ITQANAVTKTKT L ! ! +-2ld5_A ! ! --SGQATT--CTRG--LTNT--------RCVACTNAQA---- L -17 ! +---------------2xsd_C ! ! +------12 AT--QAAT--SA------------------------------ ! +--15 +---------------4z5h_A ! ! ------------------------------LARTETQT---- L ! +-----------------------7m5w_A ! ----QASTCTSARTET-------------------------- L +----------------------------5j2y_A |
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updated Fri Sep 13 15:32:15 2024