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structure nameCRYSTAL STRUCTURE OF THE HOMEODOMAIN OF PLATYPUS SDUX IN COMPLEX WITH DNA CONTAINING 5-BROMOURACIL
(Homeobox domain-containing protein)
referenceAihara et al. Iscience 26 107823 2023
sourceOrnithorhynchus anatinus
experimentX-ray (resolution=2.17, R-factor=0.240)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes8ejo_AB 8ejp_AB
redundant complexes8ejo_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRVQNR

Estimated binding specificities ?

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# IC=3.142 IC/col=0.786 n_of_columns=4 specificity:   
A |  54   0   0  57
C |  13   0  96  13
G |  16   0   0  13
T |  13  96   0  13
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --RC--IAQCNAYC--   L         +-----------------------------3rkq_B    
                             +-2 
  RART--VTKGNA--KA   L     +-3 +-----------------------------2lkx_A    
                           ! ! 
  --RT--IAQCNAMG--   L   +-4 +-----------------------------1b72_A    
                         ! ! 
  --RTQTVAQTNA----   L   ! !                            +8osb_E    
                       --5 +----------------------------1 
  ------NCICNARGRG   L   !                              +4xrm_B    
                         ! 
  --RTYTNC--NAKG--   L   +-----------------------------8pi8_B    
                       

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updated Wed Dec 18 16:59:47 2024