8ejp_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HOMEODOMAIN OF PLATYPUS SDUX IN COMPLEX WITH DNA CONTAINING 5-BROMOURACIL (Homeobox domain-containing protein)
reference	Aihara et al. Iscience 26 107823 2023
source	Ornithorhynchus anatinus
experiment	X-ray (resolution=2.17, R-factor=0.240)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	8ejo_AB 8ejp_AB
redundant complexes	8ejo_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ejp_B interface=2,5,47,50,51,55, aRrkRttfnktqleilvksfnkdpypgigvrehlasliqipesriqVwfQNrraRq
interface signature	RRVQNR

Estimated binding specificities ?

readout + contact

# IC=5.567 IC/col=0.464 n_of_columns=12

specificity:

A |   0   0  96   0  24  42  24  24  24  24  24  21
C |   0   0   0   0  24  23  24  24  24  24  24  44
G |   0  96   0   0  24  21  24  24  24  24  24  21
T |  96   0   0  96  24  10  24  24  24  24  24  10

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --RC--IAQCNAYC--   L       +-----------------------------3rkq_B    
                           +-3 
  RART--VTKGNA--KA   L     ! +-----------------------------2lkx_A    
                         +-4 
  --RT--IAQCNAMG--   L   ! !                        +----1b72_A    
                         ! +------------------------2 
  --RTQTVAQTNA----   L --5                          !   +8osb_E    
                         !                          +---1 
  ------NCICNARGRG   L   !                              +4xrm_B    
                         ! 
  --RTYTNC--NAKG--   L   +-----------------------------8pi8_B

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updated Sat Sep 14 09:52:00 2024