interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE COMPLEX OF HMG-D AND DNA
(HIGH MOBILITY GROUP PROTEIN D)
referenceChurchill et al. 'EMBO 18 6610 1999
sourceDrosophila melanogaster
experimentX-ray (resolution=2.20, R-factor=0.238)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
multimeric complexes1qrv_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSYMLRVTA

Estimated binding specificities ?

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# IC=4.887 IC/col=0.815 n_of_columns=6 specificity:   
A |  19  24   0  96   0   0
C |  19  24   0   0   0  76
G |  38  24   0   0   0   0
T |  20  24  96   0  96  20
scan!

Dendrogram of similar interfaces ?

matrix format
  
  KCRC--YTMALTRA--VCTG--AAVCEC   L                       +-1qrv_A    
                                                 +-------1 
  --RC--FAFTCG----IC--VGAG----   L          +----2       +-2gzk_A    
                                            !    ! 
  --RGNTFTMA--RT--NGRT--SA----   L   +------3    +---------7m5w_A    
                                     !      ! 
  --RCNTFTMA--RAHGNT----SA----   L --4      +--------------3f27_D    
                                     ! 
  ------YA--------FT----SG----       +---------------------5ze0_N

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updated Sun Aug 3 05:52:46 2025