interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE HMG-C1 DOMAIN OF HUMAN CAPICUA BOUND TO DNA
(PROTEIN CAPICUA HOMOLOG)
referenceDowling et al. Biorxiv ? ? 2022
sourceHOMO SAPIENS
experimentX-ray (resolution=2.95, R-factor=0.211)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNFMRNRSWNLREQ

Estimated binding specificities ?

readout + contactlogo
# IC=6.915 IC/col=0.988 n_of_columns=7 specificity:   
A |  12   0  96  96   0   0  60
C |  12  12   0   0   0   0  12
G |  12  84   0   0   0  96  12
T |  60   0   0   0  96   0  12
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RGNTFTMA--RT--NGRT--SA------------WANTLARTETQT   L         +--------------7m5w_A    
                                                       +-----3 
  RCNTFTMA--RAHGNT----SA------------YA----------   L   !     !              +3f27_D    
                                                       !     +--------------1 
  RCNAFTIA--RG--NC----SA--LT----YAKT------------   L --4                    +2gzk_A    
                                                       ! 
  RC--YTMALTRA--VCTG--AA----VCEC----------------   L   !          +---------1qrv_A    
                                                       +----------2 
  ----YA------------FT--SG----------------------                  +---------5ze0_N    
                                                     

home
updated Sat Sep 14 03:15:21 2024