3f27_D : 3D-footprint complex

structure name	STRUCTURE OF SOX17 BOUND TO DNA (Transcription factor SOX-17)
reference	Palasingam et al. J.Mol.Biol. 388 619 2009
source	Mus musculus
experiment	X-ray (resolution=2.75, R-factor=0.243)
structural superfamily	HMG-box;
sequence family	HMG high mobility group box;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3f27_D interface=3,6,8,9,16,27,28,32,70, irRpmNaFMvwakdeRkrlaqqnpdlHNaelSkmlgkswkaltlaekrpfveeaerlrvqhmqdhpnykYrprr
interface signature	RNFMRHNSY

Estimated binding specificities ?

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# IC=6.234 IC/col=1.039 n_of_columns=6

specificity:

A |  96   0  96  96   0  38
C |   0  96   0   0  19  20
G |   0   0   0   0   0  19
T |   0   0   0   0  77  19

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Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: SOX17
CACAATG	PubMed	3f27_D(7.85e-06)
CCAAT	PubMed	3f27_D(4.30e-04)

Dendrogram of similar interfaces ?

matrix format

  
  RTNTFTMARANGAC--STYA   L                        +4s2q_D    
                                                +-1 
  --NAFTIARC--SGICSTYA   L   +------------------2 +1hry_A    
                             !                  ! 
  RTSAYCMT--FT--------   L --3                  +-1j5n_A    
                             ! 
  RTNTFTMARANASC--STYA   L   +--------------------1o4x_B

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updated Mon Jun 29 16:01:54 2026