1yo5_C : 3D-footprint complex

structure name	ANALYSIS OF THE 2.0A CRYSTAL STRUCTURE OF THE PROTEIN-DNA COMPLEX OF HUMAN PDEF ETS DOMAIN BOUND TO THE PROSTATE SPECIFIC ANTIGEN REGULATORY SITE (SAM pointed domain containing ets transcription factor)
reference	Balderman et al. Biochemistry 44 7095 2005
source	Homo sapiens
experiment	X-ray (resolution=2.00, R-factor=0.205)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Etsdomain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1yo5_C interface=58,61,62,64,65,80, qpihlwqflkelllkphsygrfirwlnkekgifkiedsaqvarlwgirknrpamnydKlsRSiRQyykkgiirkpdisqRlvyqfvhp
interface signature	KRSRQR

Estimated binding specificities ?

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# IC=4.250 IC/col=0.850 n_of_columns=5

specificity:

A |  84   0   0  60  60
C |  12   0   0  12  12
G |   0  96  96  12  12
T |   0   0   0  12  12

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Dendrogram of similar interfaces ?

matrix format

  
  DCKTRG--RGYA--------   L         +-----------------------------3zp5_A    
                                 +-2 
  DCKTRGSTRGYC--------   L       ! +-----------------------------4uno_A    
                               +-3 
  ----ATNTCT----SC----   L     ! !               +-------------8hcm_A    
                             +-4 +---------------1 
  --------RG--NG------       ! !                 +-------------7dci_A    
                           --5 ! 
  ----------------KGKG   L   ! +-----------------------------5xfq_A    
                             ! 
  DCKTRG--RGYA--------   L   +-----------------------------1dux_F

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updated Mon Jun 29 14:49:48 2026