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legend  pdf

structure nameELK-1/DNA STRUCTURE REVEALS HOW RESIDUES DISTAL FROM DNA-BINDING SURFACE AFFECT DNA-RECOGNITION
(ETS-DOMAIN PROTEIN ELK-1)
referenceMarmorstein et al. Nat.Struct.Biol. 7 292 2000
sourceHomo sapiens
experimentX-ray (resolution=2.10, R-factor=?)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDKSRRY

Estimated binding specificities ?

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# IC=3.555 IC/col=0.889 n_of_columns=4 specificity:   
A |  19   0   0  20
C |  20  96  96   0
G |  19   0   0  76
T |  38   0   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: ELK-1
CCGGAAGTPubMed1dux_F(2.11e-03)

Dendrogram of similar interfaces ?

matrix format
  
  QCKT--RGAT--RGNT------   L     +-----------------------------8smh_F    
                                 ! 
  DCKT--RGST--RGYA------   L   +-3                            +4bnc_A    
                               ! !       +--------------------1 
  DCKT--RG----RGYA--KA--   L   ! +-------2                    +5jvt_A    
                             --4         ! 
  ----RGNT--RGSTATRA----   L   !         +---------------------2o6g_G    
                               ! 
  ------RC----YG------KT       +-----------------------------2acj_B    
                             

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updated Sat Jan 10 04:34:02 2026