1dux_F : 3D-footprint complex

structure name	ELK-1/DNA STRUCTURE REVEALS HOW RESIDUES DISTAL FROM DNA-BINDING SURFACE AFFECT DNA-RECOGNITION (ETS-DOMAIN PROTEIN ELK-1)
reference	Marmorstein et al. Nat.Struct.Biol. 7 292 2000
source	Homo sapiens
experiment	X-ray (resolution=2.10, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Etsdomain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1dux_F interface=54,55,57,58,61,62, vtlwqfllqllreqgnghiiswtsrdggefklvdaeevarlwglrknktnmnyDKlSRalRYyydkniirkvsgqkfvykfvsype
interface signature	DKSRRY

Estimated binding specificities ?

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# IC=4.250 IC/col=0.708 n_of_columns=6

specificity:

A |   0   0   0  60  24  12
C |  84   0   0  12  24  12
G |   0  96  96  12  24  60
T |  12   0   0  12  24  12

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Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: ELK-1
CCGGAAGT	PubMed	1dux_F(2.11e-03)

Dendrogram of similar interfaces ?

matrix format

  
  QCKT--RGAT--RGNT--------   L         +-----------------------------8smh_F    
                                     +-3 
  DCKT--RG----RGYA--KA----   L       ! +-----------------------------5jvt_A    
                                   +-4 
  DCKT--RGST--RGYA--------   L     ! !                          +--4bnc_A    
                                   ! !       +------------------1 
  ECKT--RGAT--RGNT--------   L   +-5 +-------2                  +--1pue_E    
                                 ! !         ! 
  ----RGNT--RGSTATRA------   L   ! !         +---------------------2o6g_G    
                               --6 ! 
  ----------------------KG   L   ! +-----------------------------5xfq_A    
                                 ! 
  ------RC----YG------KT--       +-----------------------------2acj_B

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updated Mon Jun 29 14:09:04 2026