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structure nameELK-1/DNA STRUCTURE REVEALS HOW RESIDUES DISTAL FROM DNA-BINDING SURFACE AFFECT DNA-RECOGNITION
(ETS-DOMAIN PROTEIN ELK-1)
referenceMarmorstein et al. Nat.Struct.Biol. 7 292 2000
sourceHomo sapiens
experimentX-ray (resolution=2.10, R-factor=?)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDKSRRY

Estimated binding specificities ?

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# IC=4.250 IC/col=0.708 n_of_columns=6 specificity:   
A |   0   0   0  60  24  12
C |  84   0   0  12  24  12
G |   0  96  96  12  24  60
T |  12   0   0  12  24  12
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Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: ELK-1
CCGGAAGTPubMed1dux_F(2.11e-03)

Dendrogram of similar interfaces ?

matrix format
  
  ----ECKT--RGATRGHTRA   L                         +---4mhg_A    
                                                 +-1 
  ------KT--RG--RGYT--   L   +-------------------2 +---4bqa_A    
                             !                   ! 
  ------KT--RG--RGYA--   L --3                   +-----4l18_B    
                             ! 
  ITRGECSCSGKG--------   L   +-------------------------5i2d_R    
                           

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updated Fri Sep 13 15:32:08 2024