interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE MATA1/MATALPHA2 HOMEODOMAIN HETERODIMER BOUND TO DNA
(PROTEIN MAT A1 HOMEODOMAIN)
referenceJohnson et al.
sourceSACCHAROMYCES CEREVISIAE
experimentX-ray (resolution=2.50, R-factor=0.225)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes1akh_AB 1le8_AB 1yrn_AB
redundant complexes1akh
reference complex1le8_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRVINMR

Estimated binding specificities ?

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# IC=4.746 IC/col=0.593 n_of_columns=8 specificity:   
A |  16  16  24   5  24   0   0  83
C |   4  23  24  83  24   0  96   5
G |  20  12  24   4  24   0   0   4
T |  56  45  24   4  24  96   0   4
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ITQCNAMC--   L           +------2r5y_A    
                   +-------2 
  IAQTNA----   L   !       ! +----6es3_K    
                 --3       +-1 
  ICQTNA----   L   !         +----5edn_J    
                   ! 
  --KC--YCFA       +--------------6p5a_B

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updated Thu Jan 8 19:29:59 2026