interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE MATA1/MATALPHA2 HOMEODOMAIN HETERODIMER BOUND TO DNA
(PROTEIN MAT A1 HOMEODOMAIN)
referenceJohnson et al.
sourceSACCHAROMYCES CEREVISIAE
experimentX-ray (resolution=2.50, R-factor=0.225)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes1akh_AB 1le8_AB 1yrn_AB
redundant complexes1akh
reference complex1le8_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRVINMR

Estimated binding specificities ?

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# IC=5.525 IC/col=0.691 n_of_columns=8 specificity:   
A |   0   0  96  24   2  21  50  57
C |   0   0   0  24   3  18  16  16
G |   0  96   0  24  89  16  16  12
T |  96   0   0  24   2  41  14  11
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ITQCNAMC--   L           +------2r5y_A    
                   +-------2 
  IAQTNA----   L   !       ! +----6es3_K    
                 --3       +-1 
  ICQTNA----   L   !         +----5edn_J    
                   ! 
  --KC--YCFA       +--------------6p5a_B    
                 

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updated Thu Sep 12 15:43:45 2024