1le8_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE MATA1/MATALPHA2-3A HETERODIMER BOUND TO DNA COMPLEX
reference	Mathias et al. Structure 10 961 2002
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	1akh_AB 1le8_AB 1yrn_AB
redundant complexes	1akh_A 1yrn_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1le8_A interface=42,43,46,47,50,51, kssispqarafleqvfrrkqslnskekeevakkcgitplqvRVwfINkrMRsk
interface signature	RVINMR

Estimated binding specificities ?

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# IC=6.292 IC/col=0.787 n_of_columns=8

specificity:

A |   7   7  75   9  24   0   0  96
C |   9   7   7  73  24   0  96   0
G |   7   9   7   7  24   0   0   0
T |  73  73   7   7  24  96   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --QTVAQTNA----   L                              +8osb_E    
                                         +--------1 
  ----IAQTNA----   L                     !        +5ego_B    
                                     +---5 
  ----VTKGNA--KA   L                 !   !       +2lkx_A    
                                     !   +-------3 
  ----NT--NAIARG   L             +---6           +1b72_B    
                                 !   ! 
  ----NCICNARGRG   L             !   !            +4xrm_B    
                       +---------7   +------------2 
  RT--NT--NAIARG   L   !         !                +4cyc_B    
                       !         ! 
  ----IAQCNAMG--   L --8         !           +----1b72_A    
                       !         +-----------4 
  ----IAQCNAYC--   L   !                     +----3rkq_B    
                       ! 
  ----VTCCNAQA--   L   +--------------------------8g87_X

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updated Sat Jan 10 04:46:19 2026