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structure nameSOLUTION NMR-DERIVED COMPLEX STRUCTURE OF HOXA13 DNA BINDING DOMAIN BOUND TO DNA
(HOMEOBOX PROTEIN HOX-A13)
sourceMUS MUSCULUS
experimentNMR
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRRQIQNVKK

Estimated binding specificities ?

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# IC=8.829 IC/col=0.981 n_of_columns=9 specificity:   
A |  82  89  96   0  96  96  63  68   9
C |   1   0   0   0   0   0  27  16  13
G |   0   7   0   0   0   0   6   6   6
T |  13   0   0  96   0   0   0   6  68
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----------YAQTNAAARG--   L     +-----------------------------6wig_A    
                                 ! 
  ----------IAQCNAYA--RT   L     !                             +1nk2_P    
                                 !            +----------------2 
  ----------NT--NAITRG--         !     +------6                +5zjt_B    
                                 !     !      ! 
  --------RCVACTNAQA----   L   +-9     !      +-----------------7xrc_C    
                               ! !     ! 
  ----------VAQTNA------   L   ! !     !                       +5hod_A    
                               ! ! +---7        +--------------3 
  RA------RCVTCTNAQTRC--   L   ! ! !   !        !              +1au7_A    
                               ! ! !   !      +-4 
  ----------ITQCNAACRG--   L   ! ! !   !      ! !              +6a8r_A    
                             -10 +-8   +------5 +--------------1 
  --RT------NCSTNARG----   L   !   !          !                +1mnm_C    
                               !   !          ! 
  --------RTVAITNAMCRG--   L   !   !          +-----------------1yrn_A    
                               !   ! 
  ----TGKG--------------   L   !   +----------------------------4pxi_B    
                               !  
  ----------VAQTNA------   L   +-----------------------------1fjl_B    
                             

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updated Fri Sep 13 16:28:58 2024