interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF TALE HOMEOBOX DOMAIN TRANSCRIPTION FACTOR TGIF1 WITH ITS CONSENSUS DNA
(Homeobox protein TGIF1)
referenceMacias et al. 'Nucleic 46 9220 2018
sourceHomo sapiens
experimentX-ray (resolution=2.42, R-factor=0.207)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes6fqp_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRNINRR

Estimated binding specificities ?

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# IC=5.766 IC/col=0.961 n_of_columns=6 specificity:   
A |   0   0  96   0  54  16
C |   0   0   0  96  13  13
G |   0  96   0   0  13  54
T |  96   0   0   0  16  13
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Dendrogram of similar interfaces ?

matrix format
  
  RT--------ITQCNAMC--   L     +-----------------------------2r5y_A    
                             +-2 
  ----------VA--NAQART   L   ! !                           +-1o4x_A    
                           --3 +---------------------------1 
  ----------VTCCNAQART   L   !                             +-8g87_X    
                             ! 
  --DTRTRGTTKT--------   L   +-----------------------------2o8k_A    
                           

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updated Fri Sep 13 21:43:46 2024