6fqp_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TALE HOMEOBOX DOMAIN TRANSCRIPTION FACTOR TGIF1 WITH ITS CONSENSUS DNA (Homeobox protein TGIF1)
reference	Macias et al. 'Nucleic 46 9220 2018
source	Homo sapiens
experiment	X-ray (resolution=2.42, R-factor=0.207)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	6fqp_AB 6fqq_AB 6fqq_DE
redundant complexes	6fqq_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fqp_B interface=2,4,50,53,54,57,58, kRrRrgnlpkesvqilrdwlyehrynaypseqekallsqqthlstlqvcNwfINarRRllpdmlrk
interface signature	RRNINRR

Estimated binding specificities ?

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# IC=5.766 IC/col=0.961 n_of_columns=6

specificity:

A |  13  13   0   0   0  96
C |  54  13   0   0  96   0
G |  16  16  96   0   0   0
T |  13  54   0  96   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --RT------------NT--NA----   L         +-----------------------------1b72_B    
                                       +-2 
  RARA------------IAQTNA----   L       ! !                         +---5ego_B    
                                     +-3 +-------------------------1 
  ----RT----------NT--NAIARG   L     ! !                           +---4cyc_B    
                                   +-4 ! 
  RCRT------------VTQTNA--RG   L   ! ! +-----------------------------8ejp_B    
                                 --5 ! 
  ------------STTAQCST------       ! +-----------------------------8b4b_W    
                                   ! 
  ------STRGQTQAST----------   L   +-----------------------------7t8k_B

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updated Sat Jan 10 10:10:46 2026