| structure name | NMR STRUCTURE OF THE HOMEODOMAIN OF PITX2 IN COMPLEX WITH A TAATCC DNA BINDING SITE (PITUITARY HOMEOBOX 3) |
| source | HOMO SAPIENS |
| experiment | NMR |
| structural superfamily | Homeodomain-like; |
| sequence family | Homeobox domain; |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RRVKNK |
Estimated binding specificities ?
| readout + contact |  |
A | 0 10 96 0 12 85 10 C | 0 12 0 0 10 1 12 G | 96 64 0 0 0 10 74 T | 0 10 0 96 74 0 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: PITX2 | ||
| TAATCC | PubMed | 2lkx_A(9.63e-10) |
| TAATC | PubMed | 2lkx_A(7.97e-07) |
Dendrogram of similar interfaces ?
matrix format--KGRT----IAQCNAYA----RT-- L +1nk2_P +----------------3 --RCRT----NT--NA--ITRG---- +---------8 +5zjt_B ! ! ----RT----NT--NA--IARG---- L ! +-----------------1b72_B ! ----RT----VAQTNA---------- L ! +5hod_A ! +-------1 --RTRT----IAKGNA---------- L ! +-------5 +6m3d_C ! ! ! ----RA--RCVTCTNAQTRC------ L -11 +--7 +--------1au7_A ! ! ! ----RT--FTYAQTNAATRG------ L ! ! ! +----6ryd_F ! ! +-----------4 --------RTVAITNAMCRG------ L ! +------9 +----1yrn_A ! ! ! RC--RT--------ITQCNA--ACRG L ! ! ! +6a8r_A ! ! ! +---------------2 ------RT--NCSTNARG-------- L +-10 +--6 +1mnm_C ! ! --------RCVACTNAQA-------- L ! +----------------7xrc_C ! ----RA----YAQTNAAARG------ L +--------------------------6wig_A |
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updated Tue Dec 17 22:55:26 2024