interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.


Dendrogram of similar interfaces ?

matrix format
structure nameMITF BHLHLZ COMPLEX WITH M-BOX DNA
(MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR,METHIONYL-...)
referenceFang et al. 'To ? ? ?
sourceHOMO SAPIENS, AQUIFEX AEOLICUS VF5
experimentX-ray (resolution=3.20, R-factor=0.206)
structural superfamilyNucleic acid-binding proteins;HLH, helix-loop-helix DNA-binding domain;
sequence familyPutative tRNA binding domain; Helixloophelix DNAbinding domain;
multimeric complexes7d8t_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  ------HGNT--EC--RCRG----------   L                   +---------------7d8t_A    
                                                +------3 
  KT----HGNT--EC--RCRG----------   L            !      +---------------1nkp_A    
                                             +--6 
  ------HGNT--ET----RG----------   L         !  !     +----------------6g1l_A    
                                             !  +-----4 
  ------HGNTLGEC--RCRC----------   L         !        !                +5i50_B    
                                           +-7        +----------------1 
  ------HGNTMTEA--RCRG----------           ! !                         +1nlw_D    
                                           ! ! 
  ------HGNTLCEC--RCRG----------   L       ! !                   +-----1hlo_B    
                                         +-8 !       +-----------2 
  ------HGSTITET--RCRG----------   L     ! ! +-------5           +-----4h10_A    
                                         ! !         ! 
  --NTRGEC--RC------------------       +-9 !         +-----------------2ql2_A    
                                       ! ! ! 
  --------NTRAEC--RC------------       ! ! +---------------------------2ypa_B    
                                     -10 ! 
  --------------------QTRTWTTTKT       ! +----------------------------4gnx_B    
                                       !  
  --HG--ITEC--YCRC--------------   L   +----------------------------7f2f_B    
                                     

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updated Sat Sep 14 02:15:19 2024