7d8t_A : 3D-footprint complex

3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

Dendrogram of similar interfaces ?

matrix format

structure name	MITF BHLHLZ COMPLEX WITH M-BOX DNA (MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR,METHIONYL-...)
reference	Fang et al. 'To ? ? ?
source	HOMO SAPIENS, AQUIFEX AEOLICUS VF5
experiment	X-ray (resolution=3.20, R-factor=0.206)
structural superfamily	Nucleic acid-binding proteins;HLH, helix-loop-helix DNA-binding domain;
sequence family	Putative tRNA binding domain; Helixloophelix DNAbinding domain;
multimeric complexes	7d8t_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7d8t_A interface=12,13,16,19,20, slakerqkkdnHNliErrRRfnindrikelgtlipksndpdmrwnkgtilkasvdyirklqreqqrakelenrqkklehacrhlllriqelgiedflkvdlrvakvlsaervegsekllkltlslgdeertvvagiakyytpeelvgkkivivanlkprkifgiesqgmilaasdgenlsvivpdrdvkegaklsaale

  
  ------HGNT--EC--RCRG----------   L                   +---------------7d8t_A    
                                                +------3 
  KT----HGNT--EC--RCRG----------   L            !      +---------------1nkp_A    
                                             +--6 
  ------HGNT--ET----RG----------   L         !  !     +----------------6g1l_A    
                                             !  +-----4 
  ------HGNTLGEC--RCRC----------   L         !        !                +5i50_B    
                                           +-7        +----------------1 
  ------HGNTMTEA--RCRG----------           ! !                         +1nlw_D    
                                           ! ! 
  ------HGNTLCEC--RCRG----------   L       ! !                   +-----1hlo_B    
                                         +-8 !       +-----------2 
  ------HGSTITET--RCRG----------   L     ! ! +-------5           +-----4h10_A    
                                         ! !         ! 
  --NTRGEC--RC------------------       +-9 !         +-----------------2ql2_A    
                                       ! ! ! 
  --------NTRAEC--RC------------       ! ! +---------------------------2ypa_B    
                                     -10 ! 
  --------------------QTRTWTTTKT       ! +----------------------------4gnx_B    
                                       !  
  --HG--ITEC--YCRC--------------   L   +----------------------------7f2f_B

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updated Wed Dec 18 08:36:37 2024