| structure name | STRUCTURE OF A HOMEODOMAIN IN COMPLEX WITH DNA (Paired box protein Pax-3) |
| reference | Ladias et al. Biochemistry 48 1148 2009 |
| source | Homo sapiens |
| experiment | X-ray (resolution=1.95, R-factor=0.174) |
| structural superfamily | Homeodomain-like; |
| sequence family | Homeobox domain; |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RRVSN |
Estimated binding specificities ?
| readout + contact |  |
A | 6 75 0 6 89 6 C | 6 9 0 9 0 6 G | 75 6 0 6 6 9 T | 9 6 96 75 1 75scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: PAX3 | ||
| TAATC | PubMed | 3cmy_A(1.23e-07) |
| TAATAN | PubMed | 3cmy_A(1.13e-03) |
Dendrogram of similar interfaces ?
matrix format--RA--RT--------------VTKGNA--KA-- L +2lkx_A +-1 --KG--RT--------------IAQCNAYA--RT L +---------------5 +1nk2_P ! ! --RC--RT--------------NT--NAITRG-- +--9 +5zjt_B ! ! ------RA------------RCVTCTNAQTRC-- L ! ! +--1au7_A ! +-------------6 ------RT--------------NT--NAIARG-- L ! +--1b72_B ! ------RT--------------VAQTNA------ L ! +5hod_A +-11 +-------3 --RT--RT--------------IAKGNA------ L ! ! ! +6m3d_C ! ! +----7 RC----RT--------------ITQCNAACRG-- L ! ! ! ! +6a8r_A ! ! +----8 +-------4 ----RC----RT----------NCSTNARG---- L +-12 ! ! ! +1mnm_C ! ! +-10 ! --------------------RTVAITNAMCRG-- L ! ! ! +-------------1yrn_A ! ! ! ------RA--------------YAQTNAAARG-- L +--13 ! +------------------6wig_A ! ! ! --------------------RCVACTNAQA---- L ! ! +----------------------7xrc_C ! ! --------NGRGTGLGLC---------------- -14 ! +6vjw_A ! +-------------------------2 --------NGRGTGLGLCRG-------------- ! +7kz0_A ! RT----RT--------------VAQTNA------ L +-----------------------------1fjl_B |
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updated Fri Sep 13 16:57:20 2024