4s2q_D : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HMG DOMAIN OF THE CHONDROGENESIS MASTER REGULATOR, SOX9 IN COMPLEX WITH CHIP-SEQ IDENTIFIED DNA ELEMENT (Transcription factor SOX-9)
reference	Moovarkumudalvan et al. 'To ? ? ?
source	Mus musculus
experiment	X-ray (resolution=2.70, R-factor=0.216)
structural superfamily	HMG-box;
sequence family	HMG high mobility group box;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4s2q_D interface=5,8,10,11,18,30,31,34,72,76, phvkRpmNaFMvwaqaaRrkladqyphlhNAelSktlgklwrllnesekrpfveeaerlrvqhkkdhpdykYqprR
interface signature	RNFMRNASYR

Estimated binding specificities ?

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# IC=7.525 IC/col=1.075 n_of_columns=7

specificity:

A |  39  96   0  96  96  96   1
C |  19   0  96   0   0   0  19
G |  19   0   0   0   0   0  76
T |  19   0   0   0   0   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RTNTFTMARA--NGACST--YA--   L                           +4s2q_D    
                                                   +-----1 
  RCNAFTIARG--NC--SALTYAKT   L           +---------2     +2gzk_A    
                                         !         ! 
  RTNGFTIARA--NASGST--YAPG   L     +-----3         +-----1j46_A    
                                   !     ! 
  RGNTFTMART--NGRTSA--WANT   L   +-4     +---------------7m5w_A    
                                 ! ! 
  RCNGFTMARTHTNG--ST--YA--   L --5 +---------------------6t90_L    
                                 ! 
  RCNTFTMARAHGNAACST------   L   +-----------------------4euw_A

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updated Fri Sep 13 18:46:30 2024