| structure name | CLASSIC PROTEIN WITH A NEW TWIST: CRYSTAL STRUCTURE OF A LEXA REPRESSOR DNA COMPLEX (LexA repressor) |
| reference | Zhang et al. Nature 466 883 2010 |
| source | Escherichia coli K-12 |
| experiment | X-ray (resolution=2.29, R-factor=0.268) |
| structural superfamily | LexA/Signal peptidase;"Winged helix" DNA-binding domain; |
| sequence family | LexA DNA binding domain; Peptidase S24like; |
| multimeric complexes | 3jso_AB 3jsp_AB |
| redundant complexes |  3jsp_A
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RSPNAEE |
Estimated binding specificities ?
| readout + contact |  |
A | 2 69 24 54 0 52 0 96 0 C | 5 5 24 14 4 2 96 0 0 G | 5 17 24 20 2 37 0 0 96 T | 84 5 24 8 90 5 0 0 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: LexA | ||
| GCTACTGTATGT | PubMed | 3jso_B(2.00e-06), 3jso_AB(1.16e-03), 3jsp_A(3.07e-05) |
| TGTACAAATGTACA | PubMed | 3jso_B(1.66e-03), 3jso_AB(1.63e-10) |
| CTGTATAT | PubMed | 3jso_B(3.19e-13), 3jso_AB(9.07e-11), 3jsp_A(3.92e-06) |
| CTGTATATATACCCAG | PubMed | 3jso_B(1.64e-12), 3jsp_A(7.32e-05) |
| CTGTATATATATACAG | PubMed | 3jso_B(1.64e-12), 3jsp_AB(2.15e-04), 3jsp_A(7.32e-05) |
| GAACAGGTGTTC | PubMed | 3jsp_A(1.12e-02) |
| TACTG | PubMed | 3jsp_A(1.95e-03) |
Dendrogram of similar interfaces ?
matrix format------------------YGRG------ +-----------------------------4wcg_A +-1 QA------------------------NG +-2 +-----------------------------7k63_U ! ! --RC------------------------ +-3 +-----------------------------6l9z_S ! ! ----------------RCYG--KT---- +-4 +-----------------------------2acj_B ! ! ----------TTHT--KG------RC-- L +-5 +-----------------------------7b0c_A ! ! ----RC--------------------SG --6 +-----------------------------7cow_T ! ------SGRGPT--SGRG---------- L +-----------------------------7bhy_A |
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updated Fri Sep 13 17:18:49 2024