interface graph thumbnail
legend  pdf

structure nameEARLY B-CELL FACTOR 1 (EBF1) BOUND TO DNA
(Transcription factor COE1)
referenceGrosschedl et al. 'Genes 24 2270 2010
sourceMus musculus
experimentX-ray (resolution=2.80, R-factor=0.207)
structural superfamilyE set domains;
sequence familyIPT/TIG domain;
multimeric complexes3mln_AB 3mlo_AB 3mlp_EF
reference complex3mln_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNRNANNNSK

Estimated binding specificities ?

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# IC=6.711 IC/col=0.671 n_of_columns=10 specificity:   
A |   9   9   0   0   0  96  24  24  24   9
C |   9   9  96  96  96   0  24  24  24   9
G |  11   9   0   0   0   0  24  24  24  69
T |  67  69   0   0   0   0  24  24  24   9
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updated Thu Jan 8 22:19:21 2026