3mln_A : 3D-footprint complex

structure name	DNA BINDING DOMAIN OF EARLY B-CELL FACTOR 1 (EBF1) BOUND TO DNA (CRYSTAL FORM II) (Transcription factor COE1)
reference	Grosschedl et al. 'Genes 24 2270 2010
source	Mus musculus
experiment	X-ray (resolution=2.40, R-factor=0.173)
multimeric complexes	3mln_AB 3mlo_AB
redundant complexes	3mlo_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3mln_A interface=29,31,32,129,138,168,170,202,203,204,205, gvldantaaqsgvglarahfekqppsnlRkSNffhfvlalydrqgqpveiertafvgfvekekeansektnngihyrlqllysngirteqdfyvrlidsmtkqaivyegqdknpemcrvlltheimcsRccdkkscgNrnetpsdpviidrfflkfflkcnqnclknAgNprdmrrfqvvvsttvnvdghvlavsdnmfvhNNSKh
interface signature	RSNRNANNNSK

Estimated binding specificities ?

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# IC=7.874 IC/col=0.606 n_of_columns=13

specificity:

A |   0  24  24  24   0   0   0   0  76  67  24  24  67
C |  86  24  24  24   0   0   0   0   2   9  24  24  11
G |   0  24  24  24   0  96  96  96   9  11  24  24   9
T |  10  24  24  24  96   0   0   0   9   9  24  24   9

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Dendrogram of similar interfaces ?

matrix format

  
  RGSTNTRCNGATNA--NCNTSGKG   L                             +3mln_A    
                                 +-------------------------1 
  RGSTNTRCNCATNT--NCNTSGKG   L   !                         +3mlp_F    
                               --3 
  --------------RGATCT----   L   !                     +---3q05_D    
                                 +---------------------2 
  ----------------ATCT----                             +---3qyn_C

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updated Sun Aug 3 07:14:42 2025