3mln_A : 3D-footprint complex

structure name	DNA BINDING DOMAIN OF EARLY B-CELL FACTOR 1 (EBF1) BOUND TO DNA (CRYSTAL FORM II) (Transcription factor COE1)
reference	Grosschedl et al. 'Genes 24 2270 2010
source	Mus musculus
experiment	X-ray (resolution=2.40, R-factor=0.173)
multimeric complexes	3mln_AB 3mlo_AB
redundant complexes	3mlo_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3mln_A interface=29,31,32,129,138,168,170,202,203,204,205, gvldantaaqsgvglarahfekqppsnlRkSNffhfvlalydrqgqpveiertafvgfvekekeansektnngihyrlqllysngirteqdfyvrlidsmtkqaivyegqdknpemcrvlltheimcsRccdkkscgNrnetpsdpviidrfflkfflkcnqnclknAgNprdmrrfqvvvsttvnvdghvlavsdnmfvhNNSKh
interface signature	RSNRNANNNSK

Estimated binding specificities ?

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# IC=8.395 IC/col=0.646 n_of_columns=13

specificity:

A |  12  12  24   0  12   0   0   0  96  24  24  24   0
C |  12  18  24   6  12  96  96  96   0  24  24  24   0
G |  12  12  24   6  12   0   0   0   0  24  24  24  96
T |  60  54  24  84  60   0   0   0   0  24  24  24   0

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Dendrogram of similar interfaces ?

matrix format

  
  RGSTNTRCNGATNA--NCNTSGKG   L                             +3mln_A    
                                 +-------------------------1 
  RGSTNTRCNCATNT--NCNTSGKG   L   !                         +3mlp_F    
                               --3 
  --------------RGATCT----   L   !                     +---3q05_D    
                                 +---------------------2 
  ----------------ATCT----                             +---3qyn_C

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updated Fri Sep 13 17:25:48 2024