interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF THE SOX4 HMG DOMAIN BOUND TO DNA
(Transcription factor SOX-4)
referenceKolatkar et al. Biochem.J. 443 39 2012
sourceMus musculus
experimentX-ray (resolution=2.40, R-factor=0.238)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNFMRHNASY

Estimated binding specificities ?

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# IC=6.824 IC/col=0.975 n_of_columns=7 specificity:   
A |  96   0  96  96  10  74  10
C |   0  96   0   0  10   0  10
G |   0   0   0   0  10  10  66
T |   0   0   0   0  66  12  10
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: SOX4
CCAATPubMed3u2b_C(1.01e-03)

Dendrogram of similar interfaces ?

matrix format
  
  RTNTFTMARANGAC--STYA   L                                 +4s2q_D    
                                                         +-1 
  --NAFTIARC--SGICSTYA   L   +---------------------------2 +1hry_A    
                             !                           ! 
  RTSAYCMT--FT--------   L --3                           +-1j5n_A    
                             ! 
  RTNTFTMARANASC--STYA   L   +-----------------------------1o4x_B    
                           

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updated Mon Jun 29 17:06:29 2026