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structure nameCPG SPECIFIC METHYLTRANSFERASE IN COMPLEX WITH TARGET DNA
(Cytosine-specific methyltransferase)
referenceWojciechowski et al. Proc.Natl.Acad.Sci.USA 110 105 2013
sourceMycoplasma penetrans
experimentX-ray (resolution=2.15, R-factor=0.178)
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyC5 cytosinespecific DNA methylase;
reference complex8c59_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureVQFNSESANR

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5 specificity:   
A |  54   0   0   0  54
C |  13   0   0  96  13
G |  16  96  96   0  13
T |  13   0   0   0  16
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --VGQG--------------------------------------FGNGSGEGSCAGNGRA--   L                      +------------4dkj_A    
                                                                                 +--------1 
  ----------RTYGRG------------------DT------------KT--RG--------              +--2        +------------7ubu_A    
                                                                              !  ! 
  CC----NAVGNG----------------ECNCVC------RCRC----------------RC           +--4  +---------------------6kdb_D    
                                                                           !  ! 
  ------------------------------------------------------MC------           !  !  +---------------------6x9j_A    
                                                                         +-5  +--3 
  --------VG--PG------------------------------------------------   L     ! !     +---------------------6w8b_A    
                                                                       +-6 ! 
  ------------------STEALGMAQG----------------------------------       ! ! +---------------------------6ymv_B    
                                                                     --7 ! 
  ----------------NA--------------------------------------------   L   ! +----------------------------7n8s_A    
                                                                       ! 
  ------------------------------------TTQT----------------------       +----------------------------7dwr_B    
                                                                     

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updated Thu Sep 12 18:58:47 2024