interface graph thumbnail
legend  pdf

structure nameTCAR-SSDNA COMPLEX CRYSTAL STRUCTURE REVEALS THE NOVEL SSDNA BINDING MECHANISM OF THE MARR FAMILY PROTEINS
(TcaR transcription regulator)
referenceChen et al. 'Nucleic 42 5314 2014
sourceStaphylococcus epidermidis
experimentX-ray (resolution=3.60, R-factor=0.274)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyMarR family;
multimeric complexes4kdp_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSEKRRK

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |   0  24  16  96  13
C |  96  24  54   0  16
G |   0  24  13   0  54
T |   0  24  13   0  13
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --DCLT--AGTTRG--RG--RA----   L       +-----------------------------5h3r_A    
                                     +-1 
  ------ST--STHG------RA----   L   +-2 +-----------------------------3zpl_B    
                                   ! ! 
  TT----KATTQTTGLTRTKA--FTYT   L --3 +-----------------------------2p7c_B    
                                   ! 
  --------------YG----------       +-----------------------------3eyi_B    
                                 

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updated Sun Aug 3 08:11:58 2025