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structure nameCRYSTAL STRUCTURE OF MUTANT MARR C80S FROM E.COLI COMPLEXED WITH OPERATOR DNA
(Multiple antibiotic resistance protein MarR)
referenceZhu et al. 'J. 22 685 2017
sourceEscherichia coli
experimentX-ray (resolution=2.67, R-factor=0.203)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyMarR family;
multimeric complexes5h3r_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDLATRRR

Estimated binding specificities ?

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# IC=5.807 IC/col=0.726 n_of_columns=8 specificity:   
A |  57  24  24   0  16   0   0   0
C |  13  24  24   0  13   0  96  96
G |  13  24  24   0  13  96   0   0
T |  13  24  24  96  54   0   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  NGLTKTPTST--TT--------RT--RT--   L                                  +7el3_B    
                                                    +-----------------1 
  ET--RGTCTG--STRG----------KT--   L            +---6                 +6q2b_B    
                                                !   ! 
  --TC--KT--KGTCHT--ST----------   L            !   +-----------------7ve5_B    
                                            +---7 
  ----RGTCTA----RGNT--------RT--   L        !   !      +--------------4fx4_B    
                                            !   +------5 
  --STQTPTPG--TTRG------------HT   L        !          !        +-----5xxp_A    
                                          +-9          +--------2 
  --ST--PTTC--STQC------RA------   L      ! !                   +-----1ddn_B    
                                          ! ! 
  --TT--PTTC--STNT----------RT--   L      ! !           +-------------4lln_I    
                                          ! !  +--------4 
  ------KGTA----TA------RG------   L   +-10 +--8        +-------------1xsd_A    
                                       !  !    ! 
  --------------RC----YG--------       !  !    +----------------------2acj_B    
                                       !  !  
  --------------------YGRG------     -11  !                  +-------4wcg_A    
                                       !  +------------------3 
  --SGRGPT----SGRG--------------   L   !                     +-------7bhy_A    
                                       !  
  ------------------------KG----       +----------------------------7o4j_W    
                                     

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updated Fri Sep 13 19:43:08 2024