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structure nameHUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO RPPH1 PROMOTER
(TRANSCRIPTION FACTOR IIIB 50 KDA SUBUNIT)
referenceGuthertz et al. 'Cell(Cambridge,Mass.)' 163 1375 2015
sourceHOMO SAPIENS
experimentX-ray (resolution=2.20, R-factor=0.193)
structural superfamilyCyclin-like;
multimeric complexes4roc_AB 4rod_AB 4roe_AB 5n9g_AC 5n9g_FH 8iue_34BEPUVW 8iuh_1I 8iuh_OQ
reference complex8ity_V
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureARY

Estimated binding specificities ?

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# IC=4.007 IC/col=0.250 n_of_columns=16 specificity:   
A |  67   0  24  24  24  24  24  24  24  24  24  24  24   9   0   9
C |   9   0  24  24  24  24  24  24  24  24  24  24  24  11   0  69
G |   9  96  24  24  24  24  24  24  24  24  24  24  24   9   0   9
T |  11   0  24  24  24  24  24  24  24  24  24  24  24  67  96   9
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updated Sat Aug 2 07:15:17 2025