interface graph thumbnail
legend  pdf

structure nameHETERODIMERIC COMPLEX OF TRANSCRIPTION FACTORS MEIS1 AND DLX3 ON SPECIFIC DNA
(HOMEOBOX PROTEIN DLX-3)
referenceMorgunova et al. Nature 527 384 2015
sourceHOMO SAPIENS
experimentX-ray (resolution=3.50, R-factor=0.343)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes4xrs_BI
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  --RT------------------IAKGNA----   L                      +--------------6m3d_C    
                                                  +---------6 
  --RA----------------RCVTCTNAQTRC   L            !         !           +--1au7_A    
                                                  !         +-----------4 
  --RT------------------NT--NAITRG                !                     +--5zjt_B    
                                                  !  
  RC----RT--------------NCSTNARG--   L            !                            +1mnm_C    
                                                  !                          +-1 
  --RT------------------ITQCNAACRG   L            !            +-------------3 +6a8r_A    
                                                  !            !             ! 
  --RT------------------NT--NAIARG   L         +-12         +--7             +-1b72_B    
                                               !  !         !  ! 
  --RT------------------VAQTNA----   L         !  !         !  !               +5hod_A    
                                               !  !       +-8  +---------------2 
  --RT------------------IAQCNAYA--   L         !  !       ! !                  +1nk2_P    
                                               !  !     +-9 ! 
  --RA------------------YAQTNAAARG   L         !  !     ! ! +------------------6wig_A    
                                               !  !  +-10 ! 
  --------------------RCVACTNAQA--   L      +-13  !  !  ! +--------------------7xrc_C    
                                            !  !  !  !  !  
  ----RGTG--LG----LC--------------          !  !  +-11  +----------------------6vjw_A    
                                            !  !     !  
  --RT----------------FTYAQTNAATRG   L      !  !     !                  +----6ryd_F    
                                         +-14  !     +------------------5 
  --------------------RTVAITNAMCRG   L   !  !  !                        +----1yrn_A    
                                         !  !  !  
  --NGRGTG--LG----LCRG------------     -15  !  +---------------------------7kz0_A    
                                         !  !  
  --------YA--KTPTPG--YTRG--------   L   !  +---------------------------4mtd_D    
                                         !  
  ------------STRGQTQAST----------   L   +-----------------------------7t8k_B    
                                       

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updated Fri Sep 13 18:58:51 2024