interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF SOX18-HMG/PROX1-DNA
(Transcription factor SOX-18)
referenceNarasimhan et al. 'Nucleic 44 3922 2016
sourceMus musculus
experimentX-ray (resolution=1.75, R-factor=0.175)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNFMRNSY

Estimated binding specificities ?

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# IC=6.185 IC/col=1.031 n_of_columns=6 specificity:   
A |  19  76   0   0   0   0
C |  38   0   0   0   0   0
G |  19  19   0   0  96   0
T |  20   1  96  96   0  96
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: PROX1
CCAATPubMed4y60_C(4.51e-04)

Dendrogram of similar interfaces ?

matrix format
  
  RTNTFTMARANGAC--ST--YA   L                                 +4s2q_D    
                                                           +-1 
  --NAFTIARC--SGICST--YA   L                      +--------2 +1hry_A    
                                                  !        ! 
  RTSAYCMT--FT----------   L   +------------------3        +-1j5n_A    
                               !                  ! 
  RTNTFTMARANASC--ST--YA   L --4                  +----------1o4x_B    
                               ! 
  ----------------KTFC--       +-----------------------------8pk1_F    
                             

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updated Mon Jun 29 18:59:54 2026