4y60_C : 3D-footprint complex

structure name	STRUCTURE OF SOX18-HMG/PROX1-DNA (Transcription factor SOX-18)
reference	Narasimhan et al. 'Nucleic 44 3922 2016
source	Mus musculus
experiment	X-ray (resolution=1.75, R-factor=0.175)
structural superfamily	HMG-box;
sequence family	HMG high mobility group box;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4y60_C interface=6,9,11,12,19,31,35,73, glrirRpmNaFMvwakdeRkrlaqqnpdlhNavlSkmlgkawkelntaekrpfveeaerlrvqhlrdhpnykYrpr
interface signature	RNFMRNSY

Estimated binding specificities ?

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# IC=6.185 IC/col=1.031 n_of_columns=6

specificity:

A |  19  76   0   0   0   0
C |  38   0   0   0   0   0
G |  20  19   0   0  96   0
T |  19   1  96  96   0  96

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Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: PROX1
CCAAT	PubMed	4y60_C(4.51e-04)

Dendrogram of similar interfaces ?

matrix format

  
  RTNGFTIARA--NASGST--YAPG   L       +-----------------------------1j46_A    
                                   +-2 
  RGNTFTMART--NGRTSA--WANT   L     ! !             +---------------7m5w_A    
                                 +-3 +-------------1 
  RCNAFTIARG--NC--SALTYAKT   L   ! !               +---------------2gzk_A    
                               --4 ! 
  RCNGFTMARTHTNG--ST--YA--   L   ! +-----------------------------6t90_L    
                                 ! 
  RCNTFTMARAHGNAACST------   L   +-----------------------------4euw_A

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updated Fri Sep 13 19:02:01 2024