structure nameCRYSTAL STRUCTURE OF HUMAN HSF1 WITH HSE DNA
(Heat shock factor protein 1)
referenceHayer-Hartl et al. Nat.Struct.Mol.Biol. 23 140 2016
sourceHomo sapiens
experimentX-ray (resolution=2.91, R-factor=0.225)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyHSFtype DNAbinding;
multimeric complexes5d5v_BD 7dcj_AB 7dcs_ABC 7dcs_DEF 7dct_ABC 7dct_DEF
reference complex5hdn_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSRQMR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |   0  13   0  13
C |   0  13   0  54
G |  96  16   0  13
T |   0  54  96  16
scan!

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updated Fri Jan 9 03:02:43 2026