interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN HSF1 WITH HSE DNA
(Heat shock factor protein 1)
referenceHayer-Hartl et al. Nat.Struct.Mol.Biol. 23 140 2016
sourceHomo sapiens
experimentX-ray (resolution=2.91, R-factor=0.225)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyHSFtype DNAbinding;
multimeric complexes5d5v_BD
reference complex5d5v_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSRQMR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |   0  13   0  16
C |   0  16   0  54
G |  96  13   0  13
T |   0  54  96  13
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updated Thu Sep 12 21:04:56 2024