interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE DNA BINDING DOMAIN OF HUMAN TRANSCRIPTION FACTOR FLI1 IN COMPLEX WITH A 10-MER DNA ACCGGAAGTG
(Friend leukemia integration 1 transcription factor)
referenceTsodikov et al. Biochemistry 54 7365 2015
sourceHomo sapiens
experimentX-ray (resolution=3.45, R-factor=0.225)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDKRARY

Estimated binding specificities ?

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# IC=5.766 IC/col=0.961 n_of_columns=6 specificity:   
A |  13  13   0   0   0   0
C |  54  16   0  96  96   0
G |  13  13   0   0   0  96
T |  16  54  96   0   0   0
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updated Tue Dec 17 01:35:21 2024