5i50_B : 3D-footprint complex

structure name	STRUCTURE OF OMOMYC BOUND TO DOUBLE-STRANDED DNA (Myc proto-oncogene protein)
reference	Koelmel et al. Oncogene 36 1911 2017
source	Homo sapiens
experiment	X-ray (resolution=2.70, R-factor=0.229)
structural superfamily	HLH, helix-loop-helix DNA-binding domain;
sequence family	Helixloophelix DNAbinding domain; Myc leucine zipper domain;
multimeric complexes	5i50_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5i50_B interface=16,17,19,20,23,24, fqgamateenvkrrtHNvLErqRRnelkrsffalrdqipelennekapkvvilkkatayilsvqaetqkliseidllrkqneqlkhkleqlrnsca
interface signature	HNLERR

Estimated binding specificities ?

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# IC=3.690 IC/col=0.738 n_of_columns=5

specificity:

A |  11  18   2   0   4
C |  67  18   4   0   4
G |   9  42   2  96  84
T |   9  18  88   0   4

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ------HGNTMTEARCRG         +-----------------------------1nlw_D    
                           +-3 
  ------HGNT--ECRCRG   L   ! +-----------------------------7d8t_A    
                         --4 
  --RT----NTRGECRCQT       !                      +------2ypa_A    
                           !          +-----------1 
  ------HG----ETRTRG       +----------2           +------5v0l_A    
                                      ! 
  NTNGRTECRGRC------   L              +------------------6od3_F

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updated Sun Aug 3 09:23:10 2025