interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF OMOMYC BOUND TO DOUBLE-STRANDED DNA
(Myc proto-oncogene protein)
referenceKoelmel et al. Oncogene 36 1911 2017
sourceHomo sapiens
experimentX-ray (resolution=2.70, R-factor=0.229)
structural superfamilyHLH, helix-loop-helix DNA-binding domain;
sequence familyHelixloophelix DNAbinding domain; Myc leucine zipper domain;
multimeric complexes5i50_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHNLERR

Estimated binding specificities ?

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# IC=3.690 IC/col=0.738 n_of_columns=5 specificity:   
A |   4   0  88  18   9
C |  84  96   2  42  11
G |   4   0   2  18  67
T |   4   0   4  18   9
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------HGNTMTEARCRG         +-----------------------------1nlw_D    
                           +-3 
  ------HGNT--ECRCRG   L   ! +-----------------------------7d8t_A    
                         --4 
  --RT----NTRGECRCQT       !                      +------2ypa_A    
                           !          +-----------1 
  ------HG----ETRTRG       +----------2           +------5v0l_A    
                                      ! 
  NTNGRTECRGRC------   L              +------------------6od3_F    
                         

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updated Fri Sep 13 19:50:03 2024