| structure name | HOMO SAPIENS CCCTC-BINDING FACTOR (CTCF) ZNF5-8 AND DNA COMPLEX STRUCTURE IN SPACE GROUP P65 (Transcriptional repressor CTCF) |
| reference | Hashimoto et al. 'Mol. 66 711 2017 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.19, R-factor=0.220) |
| structural superfamily | beta-beta-alpha zinc fingers; |
| sequence family | Zinc finger, C2H2 type; |
| redundant complexes |  5k5h_A
5k5j_A
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | DYKRQTRSDV |
Estimated binding specificities ?
| readout + contact |  |
A | 9 0 66 14 0 96 0 14 0 C | 73 96 16 16 96 0 0 0 0 G | 7 0 7 59 0 0 96 82 96 T | 7 0 7 7 0 0 0 0 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: CTCF | ||
| CCCTC | PubMed | 5k5i_A(2.91e-03), 5k5j_A(2.93e-03) |
| CCCTCC | PubMed | 5k5i_A(3.53e-04), 5k5j_A(3.33e-04) |
Dendrogram of similar interfaces ?
matrix format----TCYCKARGTCQAST--TC--------RCSCDCVT-- L +--------5yef_B +--------1 --EC--SGKGRG--DG--YCKG--RG----QA--TC---- L +---3 +--------5k5h_A ! ! --------------QA----TC----RG--RGYCRT---- L +--4 +-----------------7txc_E ! ! --NT--STNAVT--QTSTSGKG--RG-------------- L --5 +---------------------6u9q_A ! NGKT--WTKG--------HTHG--RG--TGTTACNAKGRG L ! +------------1tf3_A +-----------2 RGST--YGYC----QC--TGSTRGYT-------------- +------------4is1_C |
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updated Fri Sep 13 19:57:41 2024