interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF REP-DNA COMPLEX
(Replication initiator A, N-terminal)
reference'Proc. 111 9121 2014 X-RAY DIFFRACTION
sourceStaphylococcus aureus
experimentX-ray (resolution=3.09, R-factor=0.231)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyReplication initiator protein A RepA Nter;
multimeric complexes5kbj_ABG
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERLN

Estimated binding specificities ?

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# IC=8.589 IC/col=0.859 n_of_columns=10 specificity:   
A |   4   4  96   4  24  82   4  13   0   0
C |  84  82   0   4  24   4   4  10   0  96
G |   4   4   0  84  24   6  82   4   0   0
T |   4   6   0   4  24   4   6  69  96   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------------YG--------           +-----------------------------3eyi_B    
                                 +-1 
  ----KATTQTTGLTRTKAFTYT   L   +-2 +-----------------------------2p7c_B    
                               ! ! 
  --TTSGLTYA------------   L --3 +-----------------------------2nra_C    
                               ! 
  RG--------------------       +-----------------------------8ity_V    
                             

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updated Mon Jun 29 20:18:56 2026