interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF REP-DNA COMPLEX
(Replication initiator A, N-terminal)
reference'Proc. 111 9121 2014 X-RAY DIFFRACTION
sourceStaphylococcus aureus
experimentX-ray (resolution=3.09, R-factor=0.231)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyReplication initiator protein A RepA Nter;
multimeric complexes5kbj_ABG
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERLN

Estimated binding specificities ?

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# IC=8.352 IC/col=0.835 n_of_columns=10 specificity:   
A |  11   2  96   0  24  90  11  17   0   0
C |  61  90   0   0  24   0   2  20   0  96
G |  13   2   0  96  24   4  69  25   0   0
T |  11   2   0   0  24   2  14  34  96   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------------YG--------           +-----------------------------3eyi_B    
                                 +-1 
  ----KATTQTTGLTRTKAFTYT   L   +-2 +-----------------------------2p7c_B    
                               ! ! 
  --TTSGLTYA------------   L --3 +-----------------------------2nra_C    
                               ! 
  RG--------------------       +-----------------------------8ity_V    
                             

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updated Fri Sep 13 19:58:35 2024