interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF REP-DNA COMPLEX
(Replication initiator A, N-terminal)
reference'Proc. 111 9121 2014 X-RAY DIFFRACTION
sourceStaphylococcus aureus
experimentX-ray (resolution=3.09, R-factor=0.231)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyReplication initiator protein A RepA Nter;
multimeric complexes5kbj_ABG
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERLN

Estimated binding specificities ?

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# IC=8.541 IC/col=0.854 n_of_columns=10 specificity:   
A |   0  96  61   3   3  24   3   0   3  15
C |   0   0   7  87   6  24  84   0   3   6
G |  96   0  15   3   3  24   3   0  87  72
T |   0   0  13   3  84  24   6  96   3   3
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------------YG--------           +-----------------------------3eyi_B    
                                 +-1 
  ----KATTQTTGLTRTKAFTYT   L   +-2 +-----------------------------2p7c_B    
                               ! ! 
  --TTSGLTYA------------   L --3 +-----------------------------2nra_C    
                               ! 
  RG--------------------       +-----------------------------8ity_V    
                             

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updated Sun Aug 3 09:31:17 2025