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structure nameKAISO (ZBTB33) E535Q MUTANT ZINC FINGER DNA BINDING DOMAIN IN COMPLEX WITH A DOUBLE CPG-METHYLATED DNA RESEMBLING THE SPECIFIC KAISO BINDING SEQUENCE (KBS)
(Transcriptional regulator Kaiso)
referenceMartinez-Yamout et al. Biochemistry 57 2109 2018
sourceHomo sapiens
experimentX-ray (resolution=2.32, R-factor=0.170)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex2lt7_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTSRQYNYQFRY

Estimated binding specificities ?

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# IC=2.184 IC/col=0.273 n_of_columns=8 specificity:   
A |  12  24  24  24  24   0  16  67
C |  12  24  24  24  24   0  19   9
G |  12  24  24  24  24  96  45  11
T |  60  24  24  24  24   0  16   9
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updated Thu Sep 12 22:09:21 2024