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legend  pdf

structure nameMOUSEZFP568-ZNF2-11 IN COMPLEX WITH DNA
(Zinc finger protein 568)
referencePatel et al. Cell 173 221 2018
sourceMus musculus
experimentX-ray (resolution=2.79, R-factor=0.196)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSHRYDTCSLISSHRRERCTERRERSERRHQ

Estimated binding specificities ?

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# IC=25.722 IC/col=1.072 n_of_columns=24 specificity:   
A |   0   0   0   0  10  24   0  10  96   0   0   0   0  14   0   0   0  96   0   2  71   0   0  85
C |  96  96  96   0  12  24   0  10   0  96  96  58   0  10   0  96  96   0  96   2  19  96  96   5
G |   0   0   0   0   8  24   0   8   0   0   0   0  96   8  96   0   0   0   0  87   2   0   0   2
T |   0   0   0  96  66  24  96  68   0   0   0  38   0  64   0   0   0   0   0   5   4   0   0   4
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RGSGHGRGYADCTACTST--LTITSTSTHTRG--RG--ECRA--TGECRGRG----ETRGSAECRGRGHGQT   L             +--------------5wjq_D    
                                                                                 +---------2 
  ------------------LA----TT--ECRGYGEC----RG--YCKGRGQA----TC--SC----------   L   !         +--------------8sst_A    
                                                                               --3 
  ------------------------------------SGHG--RGDAETRGRG--DCHG--------------   L   !                     +--6vtx_A    
                                                                                 +---------------------1 
  ------------------------------------TTSGRG--QCYC--NTYGQGFT--------------   L                         +--5vmz_A    
                                                                               

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updated Mon Jun 29 21:35:00 2026