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legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN KLF4 ZINC FINGER DNA BINDING DOMAIN IN COMPLEX WITH NANOG DNA
(Krueppel-like factor 4)
referenceFerreon et al. 'Nat 12 5579 2021
sourceHomo sapiens
experimentX-ray (resolution=2.14, R-factor=0.218)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex2wbs_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSHRDERRDH

Estimated binding specificities ?

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# IC=8.334 IC/col=1.042 n_of_columns=8 specificity:   
A |  24   0   0   0   0   0  24   0
C |  12   0   0   0   0   0  12   0
G |  48  96  96  96   0  96  12  96
T |  12   0   0   0  96   0  48   0
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updated Sat Aug 2 14:43:17 2025