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structure nameCRYSTAL STRUCTURE OF HUMAN KLF4 ZINC FINGER DNA BINDING DOMAIN IN COMPLEX WITH NANOG DNA
(Krueppel-like factor 4)
referenceFerreon et al. 'Nat 12 5579 2021
sourceHomo sapiens
experimentX-ray (resolution=2.14, R-factor=0.218)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex2wbs_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSHRDERRDH

Estimated binding specificities ?

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# IC=8.472 IC/col=1.059 n_of_columns=8 specificity:   
A |   0  57   0  96   0   0   0  13
C |  96  13  96   0  96  96  96  54
G |   0  13   0   0   0   0   0  16
T |   0  13   0   0   0   0   0  13
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updated Fri Sep 13 02:35:42 2024