interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF THE TWO-COMPONENT RESPONSE REGULATOR RCSB-DNA COMPLEX
(Transcriptional regulatory protein RcsB)
referenceCenter for Structural Genomics of Infectious Diseases (CSGID)
sourceEscherichia coli str. K-12 substr. MG1655
experimentX-ray (resolution=3.15, R-factor=0.186)
structural superfamilyCheY-like;C-terminal effector domain of the bipartite response regulators;
sequence familyResponse regulator receiver domain; Bacterial regulatory proteins, luxR fami; Sigma70, region 4;
multimeric complexes5vxn_CD 5w43_AB 6zix_AB 6zj2_AB
redundant complexes5vxn_C 6zix_B 6zj2_L
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIKTSSQ

Estimated binding specificities ?

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# IC=4.101 IC/col=0.820 n_of_columns=5 specificity:   
A |  10  66  86   0  85
C |  12  10  10   0  10
G |  10  10   0  96   1
T |  64  10   0   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----------ITKGTASTSAQT--   L           +------------------5w43_B    
                                   +-----1 
  FTDTITATIT--------------   L   +-2     +------------------3zh2_C    
                                 ! ! 
  ------------SCTAKTVCHTKG   L --3 +------------------------1je8_F    
                                 ! 
  ------------KGTCKGTCHT--   L   +--------------------------4wuh_B    
                               

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updated Fri Sep 13 20:39:22 2024