5w43_B : 3D-footprint complex

structure name	STRUCTURE OF THE TWO-COMPONENT RESPONSE REGULATOR RCSB-DNA COMPLEX (Transcriptional regulatory protein RcsB)
reference	Center for Structural Genomics of Infectious Diseases (CSGID)
source	Escherichia coli str. K-12 substr. MG1655
experiment	X-ray (resolution=3.15, R-factor=0.186)
structural superfamily	CheY-like;C-terminal effector domain of the bipartite response regulators;
sequence family	Response regulator receiver domain; Bacterial regulatory proteins, luxR fami; Sigma70, region 4;
multimeric complexes	5vxn_CD 5w43_AB 6zix_AB 6zj2_AB
redundant complexes	5vxn_C 6zix_B 6zj2_L
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5w43_B interface=166,167,168,170,171,172, nnmnviiaddhpivlfgirksleqiewvnvvgefedstalinnlpkldahvlitdlsmpgdkygdgitlikyikrhfpslsiivltmnnnpailsavldldiegivlkqgaptdlpkalaalqkpesvsrllekikrlspkesevlrlfaegflvteiakklnrsIKTiSSQkksammklgvendiallnylss
interface signature	IKTSSQ

Estimated binding specificities ?

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# IC=4.250 IC/col=0.850 n_of_columns=5

specificity:

A |   0   0   0  12  60
C |  12  96   0  12  12
G |   0   0   0  12  12
T |  84   0  96  60  12

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----------ITKGTASTSAQT--   L           +------------------5w43_B    
                                   +-----1 
  FTDTITATIT--------------   L   +-2     +------------------3zh2_C    
                                 ! ! 
  ------------SCTAKTVCHTKG   L --3 +------------------------1je8_F    
                                 ! 
  ------------KGTCKGTCHT--   L   +--------------------------4wuh_B

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updated Sun Aug 3 10:11:48 2025