interface graph thumbnail
legend  pdf

structure nameHUMAN PIT-1 AND 4XCATT DNA COMPLEX
(Pituitary-specific positive transcription factor 1)
referenceAgarwal et al. 'Nucleic 46 929 2018
sourceHomo sapiens
experimentX-ray (resolution=3.15, R-factor=0.233)
structural superfamilylambda repressor-like DNA-binding domains;Homeodomain-like;
sequence familyPou domain Nterminal to homeobox domain;
multimeric complexes1au7_AB 5wc9_AB 5wc9_EF
reference complex1au7_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSQTCRRVNQ

Estimated binding specificities ?

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# IC=6.192 IC/col=1.032 n_of_columns=6 specificity:   
A |  39   0   0  19  96   0
C |  19   0   0  76   0   0
G |  19   0   0   0   0   0
T |  19  96  96   1   0  96
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updated Sat Aug 2 09:45:42 2025