5xfr_B : 3D-footprint complex

structure name	TERNARY COMPLEX OF MTF2, DNA AND HISTONE (Metal-response element-binding transcription factor 2)
reference	Wang et al. Nature 549 287 2017
source	Homo sapiens
experiment	X-ray (resolution=2.25, R-factor=0.204)
structural superfamily	FYVE/PHD zinc finger;Tudor/PWWP/MBT;
sequence family	PHDfinger;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xfr_B interface=278,279, kfeegqdvlarwsdglfylgtikkinilkqscfiifedsskswvlwkdiqtcticqeeyseapnemvicdkcgqgyhqlchtphidckwlcrqcvfatttkrggalkkgpnakalqvmkqtlpysvadlewdaghktnvqqcycycggpgdwylkmlqcckckqwfheacvqclqkpmlfgdrfytficsvcssgpeylkrlplqwvdiahlclynlsvihkkkyfdselelmtyinenwdrlhpgeladtpkseryehvlealndyktmfmsgkeiKKkkhlfglrirvppvppnva
interface signature	KK

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5

specificity:

A |  13  16   0   0   0
C |  13  13  96   0   0
G |  54  54   0  96  96
T |  16  13   0   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----NGSARGHG--SC--   L                           +6el8_A    
                                                 +-1 
  ----NASTRGHT--STFT   L   +---------------------2 +1vtn_C    
                           !                     ! 
  ----NASTRTHT--STLT   L --3                     +-4lg0_A    
                           ! 
  DCKTRGST--RGYA----   L   +-----------------------4bnc_A

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updated Sat Jan 10 09:22:40 2026