5xfr_B : 3D-footprint complex

structure name	TERNARY COMPLEX OF MTF2, DNA AND HISTONE (Metal-response element-binding transcription factor 2)
reference	Wang et al. Nature 549 287 2017
source	Homo sapiens
experiment	X-ray (resolution=2.25, R-factor=0.204)
structural superfamily	FYVE/PHD zinc finger;Tudor/PWWP/MBT;
sequence family	PHDfinger;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xfr_B interface=278,279, kfeegqdvlarwsdglfylgtikkinilkqscfiifedsskswvlwkdiqtcticqeeyseapnemvicdkcgqgyhqlchtphidckwlcrqcvfatttkrggalkkgpnakalqvmkqtlpysvadlewdaghktnvqqcycycggpgdwylkmlqcckckqwfheacvqclqkpmlfgdrfytficsvcssgpeylkrlplqwvdiahlclynlsvihkkkyfdselelmtyinenwdrlhpgeladtpkseryehvlealndyktmfmsgkeiKKkkhlfglrirvppvppnva
interface signature	KK

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5

specificity:

A |   0   0   0  16  13
C |  96  96   0  54  54
G |   0   0  96  13  13
T |   0   0   0  13  16

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Dendrogram of similar interfaces ?

matrix format

  
  ------------------KGKG   L   +-----------------------------5xfq_A    
                               ! 
  ----NGSARGHG--SC------   L   !                             +6el8_A    
                             --4                          +--1 
  ----NASTRGHT--STFT----   L   !     +--------------------2  +1vtn_C    
                               !     !                    ! 
  ----NASTRTHT--STLT----   L   +-----3                    +--4lg0_A    
                                     ! 
  DCKTRGST--RGYA--------   L         +-----------------------4bnc_A

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updated Mon Jun 29 21:40:30 2026