5xfr_B : 3D-footprint complex

structure name	TERNARY COMPLEX OF MTF2, DNA AND HISTONE (Metal-response element-binding transcription factor 2)
reference	Wang et al. Nature 549 287 2017
source	Homo sapiens
experiment	X-ray (resolution=2.25, R-factor=0.204)
structural superfamily	FYVE/PHD zinc finger;Tudor/PWWP/MBT;
sequence family	PHDfinger;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xfr_B interface=278,279, kfeegqdvlarwsdglfylgtikkinilkqscfiifedsskswvlwkdiqtcticqeeyseapnemvicdkcgqgyhqlchtphidckwlcrqcvfatttkrggalkkgpnakalqvmkqtlpysvadlewdaghktnvqqcycycggpgdwylkmlqcckckqwfheacvqclqkpmlfgdrfytficsvcssgpeylkrlplqwvdiahlclynlsvihkkkyfdselelmtyinenwdrlhpgeladtpkseryehvlealndyktmfmsgkeiKKkkhlfglrirvppvppnva
interface signature	KK

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5

specificity:

A |   0   0   0  13  13
C |  96  96   0  57  54
G |   0   0  96  13  16
T |   0   0   0  13  13

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Dendrogram of similar interfaces ?

matrix format

  
  ----NASTRGHT--ST--   L                                     +2uzk_A    
                               +-----------------------------1 
  ----NASTRTHT--ST--   L     +-2                             +3l2c_A    
                             ! ! 
  ECKTRGAT--RGHT----   L   +-3 +-----------------------------4mhg_A    
                           ! ! 
  --KTRG----RGYA----   L --4 +-----------------------------4l18_B    
                           ! 
  ----NASTRGHT--STLT   L   +-----------------------------2c6y_A

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updated Sun Aug 3 10:27:50 2025