interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE SIGMA4 OF SIGMAS FUSING WITH THE RNA POLYMERASE BETA-FLAP-TIP-HELIX IN COMPLEX WITH -35 ELEMENT DNA
(RNA POLYMERASE SIGMA FACTOR RPOS,RNA POLYMERASE BETA-FLAP-...)
referenceChien et al. Proteins 88 69 2020
sourceESCHERICHIA COLI, KLEBSIELLA PNEUMONIAE
experimentX-ray (resolution=3.75, R-factor=0.226)
structural superfamilySigma3 and sigma4 domains of RNA polymerase sigma factors;
sequence familySigma70, region 4;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureLTRERRQ

Estimated binding specificities ?

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# IC=6.185 IC/col=1.031 n_of_columns=6 specificity:   
A |   0   0  19  19  96   0
C |  96   0  20   0   0  96
G |   0   0  19  76   0   0
T |   0  96  38   1   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----LTTTRGECRCRTQC--------   L     +-----------------------------4xln_F    
                                     ! 
  ----LG------TA--KGTAHTRG--   L     !                            +6jhe_A    
                                   +-4             +--------------1 
  PCFCYG------TG--MGSG--RGQC       ! !        +----2              +5zx2_F    
                                   ! !        !    ! 
  ------TTRG--AT--STQC--RG--   L --5 +--------3    +---------------2w7n_B    
                                   !          ! 
  ----------RTTC--DTSCSGKG--   L   !          +--------------------5x5l_H    
                                   ! 
  ----YA------TG--RTSGFTRC--   L   +-----------------------------6jbq_F    
                                 

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updated Fri Sep 13 21:54:41 2024