6jbx_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE FABT IN COMPLEX WITH DNA (Fatty acid biosynthesis transcriptional regulator)
reference	Chen et al. 'Febs 593 2730 2019
source	Streptococcus pneumoniae
experiment	X-ray (resolution=2.20, R-factor=0.189)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	MarR family; Penicillinase repressor 143;
multimeric complexes	6jbx_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6jbx_A interface=64,65,67,69,70,91, hhmdyqrineyltsifnnvlvieevnlrgsrfkdisikemhtidvigkapdvtpsqvskelmvTLgTvTTslnnlerkgyiervrseqdrRvvhlhltkkgrlihrlhkrfhkamvekiidgmseeeiavmgkgltnlyqfledlk
interface signature	TLTTTR

Estimated binding specificities ?

readout + contact

# IC=6.271 IC/col=0.697 n_of_columns=9

specificity:

A |  96   0  24  48   0  16  24   8  96
C |   0   0  24  16   0  16  24   8   0
G |   0   0  24  16   0   8  24  72   0
T |   0  96  24  16  96  56  24   8   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----DCLT--AGTTRGRG--RA   L                 +-----------------5h3r_A    
                                 +-----------1 
  ----ST----TC--QGRG----       +-2           +-----------------7b24_C    
                               ! ! 
  --STSTQAQGSTSART--KT--   L --3 +-----------------------------5trd_B    
                               ! 
  RT------TCTGYTRT------       +-----------------------------7vpz_N

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updated Fri Sep 13 22:09:02 2024