interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameHUMAN NUCLEOSOME CORE PARTICLE WITH H2A.X S139E VARIANT
(HISTONE H2AX)
referenceDe Falco et al. 'Nat 10 5751 2019
sourceHOMO SAPIENS
experimentX-ray (resolution=2.20, R-factor=0.232)
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes6k1i_ABCDEFGH 6k1j_ABCDEFGH 6k1k_ABCDEFGH
redundant complexes6k1i_G 6k1j
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  RT--           +-----------------------------8u14_G    
               +-1 
  RG--       +-2 +-----------------------------8txv_G    
             ! ! 
  RGRG     --3 +-----------------------------8kcb_A    
             ! 
  RT--       +-----------------------------8smw_G    
           

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updated Fri Sep 13 22:14:04 2024