6ppr_B : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF ADNA(D934A)-ADNB(D1014A) IN COMPLEX WITH AMPPNP AND DNA (UVRDREP HELICASE)
source	MYCOBACTERIUM SMEGMATIS
experiment	NMR
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
sequence family	UvrD/REP helicase;
multimeric complexes	6ppr_AB 6ppu_AB 7sjr_AB
redundant complexes	6ppu 7sjr
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6ppr_B interface=58,60,90,112,218,289,290,377,591,613, lglfpptdeqaaviaappgplvviagagagktetmaarvvwlvangfatpsqvlgltFtRkaagqllrrvrtrlarlagagesatvstyHafagtllrehglllpvepdtrLlsetelwqlaydvvcahpghldtektpaavtamvlrlsgalaehlvdtdqlrdthvelerlvhtlpagppsqwllrmlatqtertelvplidalhqrmraekvmdFgmqmaaaarlaarfpqvgeqlrqrfrvvlldeyqdtghaqrialsslfgggaddglaltavgdpiqsiygWRgasatnlprfttdfpysdgtpaptlelrtswrnppstlhvanavseearalrprircallnnvaaerdwvadhlarayhgaaavlvRrnadaapmaealtargvpvevvgllavpevadlvamlrliadptagsavmriltgprwrfgardiaalwrraveldgtadivaqaapdadtacvadaicdpgdaeryspagyerivalgreltmlrahlghplpelvaevrrvlgldaearaarpvaagwagtenldrfsdlvsdfaggasvsallayldaavevenglapaeltvrvqiltvHaakglewqvvavphlsarvfpSttqartwltdasdlppllrgdrgvpvldtsdiydrkilsdkisdhkksldqrrvdeerrllyvaitraedtlllsghhwgateskprgpseflcelktileeeiehwplrdqvvealwhvhrgaqlvaaamgwaadvdallaererp
interface signature	FRHLFWRRHS

Estimated binding specificities ?

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# IC=7.270 IC/col=1.212 n_of_columns=6

specificity:

A |   0   0   7   0   0   0
C |   0   0   7   0   0   0
G |   0   0   7  96   0   0
T |  96  96  75   0  96  96

scan!

Dendrogram of similar interfaces ?

matrix format

  
  FG--RTHGLT--FT------WTRG----RT--HT--ST----   L                   +-------------6ppr_B    
                                                         +---------1 
  ------HT----FT------WTRT----RT--HT----ETFT         +---2         +-------------3pjr_A    
                                                     !   ! 
  FTTT--HT----FTDTYT--WTRT----RT------------   L   +-3   +-----------------------2pjr_A    
                                                   ! ! 
  --------------------------------HTKT------     --4 +---------------------------2pjr_B    
                                                   ! 
  ----------LT------VT----PTET--RT----------   L   +----------------------------7otj_B

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updated Fri Sep 13 22:57:30 2024