3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.

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updated Tue Jan 6 13:48:19 2026

structure name	CENP-A NUCLEOSOME CORE PARTICLE WITH 145 BASE PAIRS OF THE WIDOM 601 SEQUENCE BY CRYO-EM
source	XENOPUS LAEVIS / HOMO SAPIENS
experiment	NMR
structural superfamily	Histone-fold;P-loop containing nucleoside triphosphate hydrolases;Chromo domain-like;Homeodomain-like;lambda repressor-like DNA-binding domains;p53-like transcription factors;
reference complex	5o9g_F 5o9g_G 5x0y_D 6c0w_A 6g0l_M 6r8y_H 6x0n_f 7nkx_f 7u0g_M 7vdt_B 7xzx_N 7ywx_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6tem_A interface= wlkeirklqksthllirklpfsrlareicvkftrgvdfnwqaqallalqeaaeaflvhlfedaylltlhagrvtlfpkdvqlarrirg > 6tem_B interface=12, dniqgitkpaiRrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 6tem_C interface=29, aktrssraglqfpvgrvhrllrkgnyaeRvgagapvylaavleyltaeilelagnaardnkktriiprhlqlavrndeelnkllgrvtiaqggvlpniqsvllp > 6tem_D interface=3, ksRkesyaiyvykvlkqvhpdtgisskamsimnsfvndvferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsak > 6tem_E interface= wlKeirklqksthllirklpfsrlareicvkftrgvdfnwqaqallalqeaaeaflvhlfedaylltlhagrvtlfpkdvqlarrirgl > 6tem_F interface= niQgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 6tem_G interface=29, aktrssraglqfpvgrvhrllrkgnyaeRvgagapvylaavleyltaeilelagnaardnkktriiprhlqlavrndeelnkllgrvtiaqggvlpniqsvll > 6tem_H interface= srkesyaiyvykvlkqvhpdtgisskamSimnsfvndvferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsa