interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE DNA BINDING DOMAIN OF HUMAN TRANSCRIPTION FACTOR FLI1 IN COMPLEX WITH 16-MER DNA CAGAGGATGTGGCTTC
(Friend leukemia integration 1 transcription factor)
referenceTsodikov et al. Structure 29 404 2021
sourceHomo sapiens
experimentX-ray (resolution=3.90, R-factor=0.249)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRRY

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |  57   0   0  96  13
C |  13   0   0   0  16
G |  13  96  96   0  13
T |  13   0   0   0  54
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updated Tue Dec 17 07:35:02 2024