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legend  pdf

structure nameZNF410 ZINC FINGERS 1-5 WITH 17 MER BLUNT DNA OLIGONUCLEOTIDE
(Zinc finger protein 410)
referenceHorton et al. Mol.Cell 81 239 2021
sourceHomo sapiens
experimentX-ray (resolution=2.75, R-factor=0.161)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureWAHYQRVTNNEYSSKQS

Estimated binding specificities ?

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# IC=13.759 IC/col=1.058 n_of_columns=13 specificity:   
A |   7  96   0   0   0   0  96   7  73  73   0  90  90
C |  16   0   0  96  96  96   0   5   5  11   0   6   1
G |  11   0   0   0   0   0   0   5   5   7   0   0   0
T |  62   0  96   0   0   0   0  79  13   5  96   0   5
scan!

Dendrogram of similar interfaces ?

matrix format
  
  WTAAHTYA----QARA--VT--TT--NA--ECYTSGST--KG----QA----SA----   L                         +--6wmi_A    
                                                                       +-----------------1 
  TTTCLA--TTSC--EC--RGYGECSCKGRGDG--YCKG--RG--TCQA----TC----   L       !                 +--5t0u_A    
                                                                   +---4 
  ----------AG--KG--RG--RGDCKG------YC----------RGSTDCHGRG--   L   !   !           +---------7eyi_G    
                                                                   !   ! +---------2 
  ------------TTSGRTRG--LTECYC--NTYGQGFT--------------------   L --5   +-3         +---------2lt7_A    
                                                                   !     ! 
  --------------YG------WTWTSTET--FTVASGDCSART--------------   L   !     +-------------------6a57_A    
                                                                   ! 
  ----------------------------------SA----------TT----NAVTRT       +------------------------7y3m_I    
                                                                 

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updated Tue Dec 19 15:53:09 2023