structure name | CTCF ZNF2-7 AND DNA COMPLEX STRUCTURE (Transcriptional repressor CTCF) |
reference | Hashimoto et al. 'Mol. 66 711 2017 |
source | Homo sapiens |
experiment | X-ray (resolution=3.20, R-factor=0.231) |
structural superfamily | beta-beta-alpha zinc fingers; |
sequence family | Zinc finger, C2H2 type; |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | TTLTSERYESKRDYKRTQTRSD |
Estimated binding specificities ?
readout + contact |
A | 64 24 8 0 0 0 0 0 0 0 0 0 16 0 0 C | 8 24 16 96 0 96 96 96 96 96 0 0 80 8 0 G | 16 24 16 0 96 0 0 0 0 0 0 96 0 8 96 T | 8 24 56 0 0 0 0 0 0 0 96 0 0 80 0scan! |
Dendrogram of similar interfaces ?
matrix format--TTTCLA--------TTSC--EC--RGYG--EC--SCKGRG--DG--YCKG--RGTCQA----TC------RASCDC-- L +--5t0u_A +-----2 ----SGHG--RG--RGDC--SCHG--------DC--SANA----WC--SCVG--RG--DC--SGNA--------STHGRG L +----------5 +--5v3g_A ! ! --------------------------------EC--SGKGRG--DG--YCKG--RG--QA----TC------RASCDCVT L +-8 +--------5k5h_A ! ! --------RG--YG--EC--SCKG--RG------TCYCKARGTCQAST--TC------RC--SCDC--VT---------- L ! ! +-------5yef_B +-9 +-----------4 --------------------------------DC--YCKGRG--QA----TC------RC--SCDC--VT---------- L ! ! +-------5k5i_A ! ! ----------------DC--SCQG--KT--TTAT--SCSC----DC--SGATRARG--RG--DCNA-------------- L ! +---------------------6ml4_A +-10 --ECSCKG--RG----DCTCYCKG--RG----QA----TC----RC--SCDC--VT------------------------ L ! ! +-------------5und_A ! ! +--6 ------------------------------FT----KAYT----WT--WTST--ET--FTVASGDCSARG---------- L ! ! ! ! +---6jnm_A ! +------7 +---------3 ------------------------------NGKT--WTKG--------HTHG--RGTGTT--ACNA--KGRG-------- L +--11 ! +---1tf3_A ! ! ! --------------------------------------YG----WT--WTST--ET--FTVASGDCSART---------- L ! ! +----------------6a57_A ! ! RGSTYGYC--------QC--TGSTRAYT---------------------------------------------------- L -12 ! +3uk3_C ! +-----------------------1 --------------------------------------------NT--STNA--VT--QTSTSGKG--RG---------- L ! +6u9q_A ! ------------------------------------TCSGRG--LT--ETYC------NTYGQG---------------- L +---------------------------6dfb_A |
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updated Thu Dec 22 22:03:23 2022