6a57_A : 3D-footprint complex

structure name	STRUCTURE OF HISTONE DEMETHYLASE REF6 COMPLEXED WITH DNA (Lysine-specific demethylase REF6)
reference	Tian et al. 'Cell 6 17 2020
source	Arabidopsis thaliana
experiment	X-ray (resolution=2.70, R-factor=0.223)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
multimeric complexes	6jnn_AN
reference complex	6jnm_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6a57_A interface=58,85,87,88,91,115,116,117,118,120,121, ekeeeeeeeeneeeecaayqcnmegctmsfssekqlmlhkrnicpikgcgknffshkYlvqhqrvhsddrplkcpwkgckmtfkWaWSrtEhirvhtgarpyvcaepdcgqtfrFVSDfSRhkrktghsvk
interface signature	YWWSEFVSDSR

Estimated binding specificities ?

readout + contact

# IC=6.445 IC/col=1.074 n_of_columns=6

specificity:

A |  38   0  96  19  96   0
C |  38  96   0   0   0   0
G |  20   0   0  76   0  96
T |   0   0   0   1   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----YG----WT--WTSTETFTVASGDCSART   L            +----------------6a57_A    
                                           +------1 
  --------RGST--YGYC--QC--TGSTRGYT       +-2      +----------------4is1_C    
                                         ! ! 
  NTSTNAVT--QTSTSGKGRG------------   L --3 +-----------------------6u9q_A    
                                         ! 
  ----------QA----TCRGRG--YCRT----   L   +-------------------------7txc_E

home
updated Fri Jan 9 05:20:13 2026