interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF HISTONE DEMETHYLASE REF6 COMPLEXED WITH DNA
(Lysine-specific demethylase REF6)
referenceTian et al. 'Cell 6 17 2020
sourceArabidopsis thaliana
experimentX-ray (resolution=2.70, R-factor=0.223)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYWWSEFVSDSR

Estimated binding specificities ?

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# IC=6.410 IC/col=1.068 n_of_columns=6 specificity:   
A |   0   0   0   0   0  38
C |  96   0  76   0   0  38
G |   0   0   1   0  96  19
T |   0  96  19  96   0   1
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----YG----WT--WTSTETFTVASGDCSART   L            +----------------6a57_A    
                                           +------1 
  --------RGST--YGYC--QC--TGSTRGYT       +-2      +----------------4is1_C    
                                         ! ! 
  NTSTNAVT--QTSTSGKGRG------------   L --3 +-----------------------6u9q_A    
                                         ! 
  ----------QA----TCRGRG--YCRT----   L   +-------------------------7txc_E    
                                       

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updated Fri Sep 13 21:14:15 2024