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structure nameHEME SENSOR PROTEIN PEFR FROM STREPTOCOCCUS AGALACTIAE BOUND TO OPERATOR DNA (28-MER)
(HTH marR-type domain-containing protein)
referenceNishinaga et al. 'Commun 4 467 2021
sourceStreptococcus agalactiae serotype III (strain NEM316) / Streptococcus agalactiae serotype III (strain NEM316)
experimentX-ray (resolution=2.49, R-factor=0.219)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyMarR family;
multimeric complexes7dvv_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSKSVSNKRR

Estimated binding specificities ?

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# IC=8.936 IC/col=0.993 n_of_columns=9 specificity:   
A |  96   0  56   0   0   0  96   8  16
C |   0   0   8   0   0   0   0   8  48
G |   0   0  16  96   0   0   0   8  16
T |   0  96  16   0  96  96   0  72  16
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----RGSTRTSTHG--------RA----   L         +-----------------------------3zpl_B    
                                         +-1 
  --DCLT--AGTTRG----RG--RA----   L     +-2 +-----------------------------5h3r_A    
                                       ! ! 
  TT----KATTQTTG--LTRTKA--FTYT   L   +-3 +-----------------------------2p7c_B    
                                     ! ! 
  ----------------YG----------     --4 +-----------------------------3eyi_B    
                                     ! 
  ----------NCTTNAVTNT--------   L   +-----------------------------1pp7_U    
                                   

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updated Wed Dec 18 08:39:11 2024