7el1_A : 3D-footprint complex

structure name	STRUCTURE OF A PROTEIN FROM BACTERIA (CRISPR-ASSOCIATED ENDONUCLEASE CAS9)
reference	Huang et al. 'Nucleic 49 6587 2021
source	STAPHYLOCOCCUS AUREUS
experiment	X-ray (resolution=2.22, R-factor=?)
structural superfamily	Ribonuclease H-like;
multimeric complexes	8jg9_ACF
redundant complexes	5axw 5czz
reference complex	7vw3_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7el1_A interface=866,966,967,970,972,994,996, rnyilgldigitsvgygiidyetrdvidagvrlfkeanvennegrrskrgarrlkrrrrhriqrvkkllfdynlltdhselsginpyearvkglsqklseeefsaallhlakrrgvhnvneveedtgnelstkeqisrnskaleekyvaelqlerlkkdgevrgsinrfktsdyvkeakqllkvqkayhqldqsfidtyidlletrrtyyegpgegspfgwkdikewyemlmghctyfpeelrsvkyaynadlynalndlnnlvitrdenekleyyekfqiienvfkqkkkptlkqiakeilvneedikgyrvtstgkpeftnlkvyhdikditarkeiienaelldqiakiltiyqssediqeeltnlnseltqeeieqisnlkgytgthnlslkainlildelwhtndnqiaifnrlklvpkkvdlsqqkeipttlvddfilspvvkrsfiqsikvinaiikkyglpndiiielareknskdaqkminemqkrnrqtnerieeiirttgkenakyliekiklhdmqegkclysleaipledllnnpfnyevdhiiprsvsfdnsfnnkvlvkqeeaskkgnrtpfqylsssdskisyetfkkhilnlakgkgrisktkkeylleerdinrfsvqkdfinrnlvdtryatrglmnllrsyfrvnnldvkvksinggftsflrrkwkfkkernkgykhhaedaliianadfifkewkkldkapeieteqeykeifitphqikhikdfkdykyshrvdkkpnrelindtlystrkddkgntlivnnlnglydkdndklkklinkspekllmyhhdpqtyqklklimeqygdeknplykyyeetgnyltkyskkdngpvikkikyygNklnahlditddypnsrnkvvklslkpyrfdvyldngvykfvtvknldvikkenyyevnskayeeakklkkisnqaefiasfynndlikingelyrvigvNNdlLnRievnmidityreylenmndkrPpRiiktiasktqsikkystdilgnlyevkskkhpqiikk
interface signature	NNNLRPR

Estimated binding specificities ?

readout + contact

# IC=5.807 IC/col=0.968 n_of_columns=6

specificity:

A |  16  96   0  13   0  96
C |  13   0   0  13  96   0
G |  13   0   0  13   0   0
T |  54   0  96  57   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --LAYA--MTTG--NG--KGDG--DC----NT--RGYG--------   L       +---------6je3_A    
                                                       +---2 
  ----YC--LG--NT------EG--TA--SATT--ST------KTSG   L   !   +---------5x2h_A    
                                                     --3 
  RA----RC--------QA--EA----EC----KGRA----RGRG--   L   !      +------6wbr_A    
                                                       +------1 
  --------RC--------KCEGFT----------KARGRGPTLT--   L          +------6joo_A

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updated Tue Dec 17 09:10:59 2024