interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF FOXP3-DNA COMPLEX
referenceLeng et al. Immunity 55 1354 2022
experimentX-ray (resolution=4.00, R-factor=0.336)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNRHS

Estimated binding specificities ?

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# IC=4.691 IC/col=0.782 n_of_columns=6 specificity:   
A |   0  16   5   0  19  83
C |   0   6   4   0  12   5
G |   0  54   4   0  20   4
T |  96  20  83  96  45   4
scan!

Dendrogram of similar interfaces ?

matrix format
  
  KGQG----------------------                                       +-8h7a_A    
                                       +---------------------------1 
  --------TCTG--YTRT--------         +-2                           +-7vpz_N    
                                     ! ! 
  ----FGTTPTRTAT----LT------   L   +-3 +-----------------------------4hqe_A    
                                   ! ! 
  ----DTRTRGTT----KT--------   L --4 +-----------------------------2o8k_A    
                                   ! 
  ------------KT----RGSTRGYC   L   +-----------------------------4uno_A    
                                 

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updated Tue Dec 19 20:45:16 2023