interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF FOXP3-DNA COMPLEX
referenceLeng et al. Immunity 55 1354 2022
experimentX-ray (resolution=4.00, R-factor=0.336)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNRHS

Estimated binding specificities ?

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# IC=4.737 IC/col=0.790 n_of_columns=6 specificity:   
A |   0  18   4   0  20  83
C |   0  20   4   0  15   4
G |   0  54   4   0  16   4
T |  96   4  84  96  45   5
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------NASTRGHT--STLT--------   L                          +------7cby_C    
                                                  +-----------1 
  --ST----NASTRTHT--ST----------   L          +---2           +------3l2c_A    
                                              !   ! 
  ------RTSTHG------------RA----   L   +------3   +------------------3zpl_B    
                                       !      ! 
  TT--KATTQTTG--LTRT----KA--FTYT   L --4      +----------------------2p7c_B    
                                       ! 
  --------------YG--------------       +-----------------------------3eyi_B    
                                     

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updated Wed Dec 18 11:19:58 2024