interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF FOXP3-DNA COMPLEX
referenceLeng et al. Immunity 55 1354 2022
experimentX-ray (resolution=4.00, R-factor=0.336)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNRHS

Estimated binding specificities ?

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# IC=4.985 IC/col=0.831 n_of_columns=6 specificity:   
A |   0  68  96  73   7  96
C |   8   7   0   7  68   0
G |   7   7   0   7  14   0
T |  81  14   0   9   7   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------NASTRGHT--STLT--------   L                          +------7cby_C    
                                                           +--1 
  --ST----NASTRTHT--ST----------   L               +-------2  +------3l2c_A    
                                                   !       ! 
  ------RTSTHG------------RA----   L   +-----------3       +---------3zpl_B    
                                       !           ! 
  TT--KATTQTTG--LTRT----KA--FTYT   L --4           +-----------------2p7c_B    
                                       ! 
  --------------YG--------------       +-----------------------------3eyi_B    
                                     

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updated Sat Sep 14 04:39:15 2024