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legend  pdf

structure nameSTRUCTURE OF FOXG1 DNA BINDING DOMAIN BOUND TO DBE2 DNA SITE
(Forkhead box protein G1)
referenceChen et al. J.Mol.Biol. 432 6146 2020
sourceHomo sapiens
experimentX-ray (resolution=1.65, R-factor=0.158)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHSL

Estimated binding specificities ?

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# IC=5.339 IC/col=0.890 n_of_columns=6 specificity:   
A |   9   9  11   0   0  96
C |  11   9   9   0   0   0
G |   9  69   9   0   0   0
T |  67   9  67  96  96   0
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Dendrogram of similar interfaces ?

matrix format
  
  ----------------NAST--RGHT--STLT--------   L                       +------7cby_C    
                                                         +-----------1 
  ------ST--------NAST--RTHT--ST----------   L       +---2           +------3l2c_A    
                                                     !   ! 
  ----------RGSTRTSTHG--------------RA----   L     +-3   +------------------3zpl_B    
                                                   ! ! 
  RT--LA--NTHGTTETYTRG--------------------   L   +-4 +----------------------1f4k_B    
                                                 ! ! 
  --TT--------KATTQTTG----LTRT----KA--FTYT   L --5 +------------------------2p7c_B    
                                                 ! 
  --------------KT--RGAT--RGNT------------   L   +--------------------------8smh_F    
                                               

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updated Wed Dec 18 08:20:11 2024