7cby_C : 3D-footprint complex

structure name	STRUCTURE OF FOXG1 DNA BINDING DOMAIN BOUND TO DBE2 DNA SITE (Forkhead box protein G1)
reference	Chen et al. J.Mol.Biol. 432 6146 2020
source	Homo sapiens
experiment	X-ray (resolution=1.65, R-factor=0.158)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Fork head domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7cby_C interface=51,52,54,55,58,59, pkyekppfsynalimmairqspekrltlngiyefimknfpyyrenkqgwqNSiRHnlSLnkcfvkvprhyddpgkgnywmldpssddvfiggttgklrrr
interface signature	NSRHSL

Estimated binding specificities ?

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# IC=5.339 IC/col=0.890 n_of_columns=6

specificity:

A |  11   9   9   0   0  96
C |   9   9   9   0   0   0
G |   9  69  11   0   0   0
T |  67   9  67  96  96   0

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Dendrogram of similar interfaces ?

matrix format

  
  ----------------NAST--RGHT--STLT--------   L                      +-------7cby_C    
                                                                  +-1 
  ------ST--------NAST--RTHT--ST----------   L             +------2 +-------3l2c_A    
                                                           !      ! 
  ----------RGSTRTSTHG--------------RA----   L         +---3      +---------3zpl_B    
                                                       !   ! 
  RT--LA--NTHGTTETYTRG--------------------   L   +-----4   +----------------1f4k_B    
                                                 !     ! 
  --TT--------KATTQTTG----LTRT----KA--FTYT   L --5     +--------------------2p7c_B    
                                                 ! 
  --------------KT--RGAT--RGNT------------   L   +--------------------------8smh_F

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updated Sat Sep 14 02:01:52 2024