| structure name | CRYSTAL STRUCTURE OF HUMAN DNMT1(646-1600) IN COMPLEX WITH DNA (DNA cytosine-5-methyltransferase 1) |
| reference | Patel et al. Science 331 1036 2011 |
| source | Homo sapiens |
| experiment | X-ray (resolution=3.60, R-factor=0.257) |
| structural superfamily | S-adenosyl-L-methionine-dependent methyltransferases; |
| sequence family | BAH domain; C5 cytosinespecific DNA methylase; CXXC zinc finger domain; |
| reference complex | 6x9j_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence |
No structural evidence for specific binding to DNA (<4 informative columns)
Dendrogram of similar interfaces ?
matrix format------SGKGQC---------------------------------------------------------------------- +------------3pta_A +-------------4 ----------------------------------------FGNG--------------HGNA------EGMC--KGQG---- L ! ! +4da4_B +-7 +------------1 ----------------------------NT--------VT--------------------------------------LG-- ! ! +6pa7_K ! ! --------------------------------------------------------SG------------------------ ! +--------------------------3ubt_A ! ------------------------------------IT--------------------------ECRG----AT-------- +-8 +----5ciy_A ! ! +-------2 --------------------------------------------------------------EG----SCAGNG-------- L ! ! +-----------3 +----4dkj_A ! ! ! ! --------------------------CC----NGPG------------ECNCVCRC------------------------RC +-9 +--6 +------------6kdb_D ! ! ! ------------------------------------IA-------------------------------------------- L ! ! +------------------------6w8b_A +-10 ! --------------FTDTITVT--AT----KA------------LGIT---------------------------------- L ! ! +----------------------------3zh2_C ! ! ----------------------NA--YA------------------------------------------------------ L +-11 ! +-------------------2ih2_D ! ! +---------5 ----------------------NA--FA------------------------------------------------------ ! ! +-------------------2y7h_B -12 ! RCNTICKGKGQGKT-------------------------------------------------------------------- L ! +-----------------------------2kkf_A ! ------KTKGQC---------------------------------------------------------------------- L +-----------------------------4nw3_A |
home
updated Thu Sep 12 17:53:43 2024